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CAM THERAPIES

 

         Complementary (alternative therapies used with modern medical system treatments) and Alternative (used instead of modern medical system treatments) are collectively termed “CAM Therapies”.  While the use of these therapies is growing, as of 2012, 18% of the population used natural products (supplements, herbs, vitamins), 11% used deep breathing techniques, 10% Yoga, Tai Chi or Qi Gong, 8% chiropractic or osteopathic manipulation, 8% meditation, 7% massage, 2% homeopathy, 2% progressive relaxation, and 2% guided imagery.  

         CAM therapies have in the past had relatively little research into their outcomes but an effort by the US Government and researchers around the US have demonstrated some of the treatments have proven benefit, albeit usually measurably small benefits.  Much of the research done by CAM therapists from 1990 to today do not meet the minimum study design standards to be considered proof.  Most are of the type “I did this technique and they got better”, not using any comparative group, control group, and the studies are enormously biased since the person performing the techniques have economic incentive for the technique to show positive results.  In some cases such as Chinese studies, most of the results and reviews of techniques are absurdly positive, not reproducible in any other environment other than China, and are not a pure evaluation of a technique (in Chinese medicine, multiple techniques are used simultaneously).  Therefore we discount studies performed in China as non-scientific and inherently biased.

         CAM Therapies are divided into 1. Medical systems (such as Ayurvedic, Traditional Chinese, Anthrosophic, Chiropractic, Homeopathy, Naturopathy, etc),  2. Substances (including chemicals sold as supplements, vitamins, herbs, essential oils, etc)  3. Bodywork (such as massage, aquatherapy, tai chi, etc)   4. Mindwork (hypnosis, meditation, etc. )  5. Energy therapies. 

         A summary of the major techniques in CAM medicine is found below along with scientific documentation if available.  The lack of scientific documentation does not mean a therapy does not work, but that it has not been tested and is simply speculative.  Many CAM therapies are speculative, and advertising for these are based on testimonials (individuals claiming great relief), historical use (has been used for hundreds of years), or claims based on animal or lab studies that have never been used in humans.  Therefore, many of the therapies are speculative, experimental, and do not rise to the standards of care required by the medical system in the US.  Testimonials are largely fabricated or based on placebo response.  Historical means there is a tradition of use, not that the treatment works.  Animal studies or lab studies do not translate directly into human results due to our different anatomies and physiologies.  These therapies are mainly unregulated or nearly unregulated by any authority or agency, and the safety or effectiveness of these therapies do not require proof.  They do result in injury and death, regardless of their claims of “safety”, but as they are unregulated, there is nothing that will be done to protect the population against their use except in extreme cases.

         Levels of evidence from highest to lowest used in this monograph are:

alpha level- systematic reviews of randomized controlled trials: these may uncover poor construction, biases, high dropout rates, statistical analysis aberrations, etc. that reduce the values of randomized controlled trials.

beta level- individual randomized controlled trials, 

gamma level- non-randomized trials with case controls, 

delta level- case series uncontrolled (frequently used in alternative medicine- no placebo control, sham control or comparative group; these types of studies are subject to extreme bias of the author since most of the data is collected and analyzed by the same person doing the trial, and without a control, placebo factors are of unknown significance but statistically play a role in 30-40% of trials.

epsilon level- case reports,

zeta level- animal experiments or lab studies, 

omega level- theoretical only, no evidence. 

The presence of alpha level evidence (for or against a procedure) is more important than everything below that level of evidence.  The lack of alpha evidence for or against a procedure or technique does not invalidate the intervention, but the next level down evidence is then weighted.  Most modern medical evidence is alpha or beta level.  Most alternative therapy evidence is delta, epsilon, or omega level.  But where higher levels of evidence exist for CAM therapies, they are presented here.  Sources of scientific studies information: National Library of Medicine

 

CAM THERAPIES REVIEW

Active release technique-a registered trademark, calls itself “The Gold Standard in Soft Tissue Treatment”.  It is a technique patented by a chiropractor, that allegedly uses the hands to determine texture, tightness, and movement of the muscles, fascia, tendons, ligaments and nerves then uses 500 specific unique movements to correct the problems in addition to precisely directed tension with very specific patient movements.  It is touted as being painful by some patients descriptions as the practitioner using their fingers and thumbs trying to get under the muscle and lift it off the body.   Aetna describes it as being “similar to some massage techniques, albeit more aggressive”  Painbytes evaluation: Because it remains unproven with evidence based medicine and involves a scientifically questionable diagnostic technique, the technique garners a one thumb down.  It is considered experimental by Aetna insurance.   www.activerelease.com

 

Acupotomy- is an acupuncture technique that uses a small needle-scalpel invented by Zhu Hanzhang  around 1985 in China.  The needle is much wider than a regular acupuncture needle, and the blade is used to break up scar tissue inside muscle or skin.  Instead of a long needle, the acupotomy needle is wider and has a round plastic head on top of the shorter needle.  It is more effective than acupuncture, and the patient is more quickly able to resume normal activities, and is more effective than control patients for chronic non-specific neck pain (Evid Based Complement Alternat Med. 2017;2017:6197308.)

Acupuncture

Acupuncture includes Chinese acupuncture, Western acupuncture, auriculotherapy (ear acupuncture), moxibustion (use of burning elements to transmit heat into the acupuncture needles), laser acupuncture (using a laser), gold thread acupuncture (placement of scores of permanent fine gold threads under the skin around joints using acupuncture needles), sonoacupuncture (use of ultrasound or tuning forks on acupuncture points), and electroacupuncture (application of electricity to the needles).  Acupuncture is an ancient art used for 3,000 years in the orient to treat many maladies.  Only recently has acupuncture been subjected to randomized trials to demonstrate effectiveness.   Most studies show benefits of acupuncture for pain control from a variety of pain sources.  However the majority of studies using sham acupuncture (not in specific acupuncture points) show nearly equal pain reduction compared to verum (true) acupuncture, suggesting acupuncture works but not on the basis of meridians or acupuncture points.  This brings into question whether there should be any acupuncture board oversight of training since randomly sticking needles into people has the same effect as a trained acupuncturist.

Sham acupuncture is equivalent to real acupuncture in many studies and meta-anlysis {PLoS One 2013 Jul31:8(7),  Am J Chin Med 2013; 41(1):1-19,  Med Acupunct 2012 Dec:24(4):233-240,    J Orthop Surg Res 2012 Oct 30;7:36,  Pain 2012 Sep:153(9):1883-9, 

Ineffective for knee chronic knee pain RCT (JAMA 2014, Oct 1;312(13):1313-1322)

Ineffective for fibromyalgia (Meta-analysis) J. Tradit Chin Med 2014 Aug;34(4):381-91

Auricular therapy slightly effective for pain: meta-analysis (1.59 improvement on 1-10 scale of pain)  Evid Based Complement Alternat Med 2014:934670

 

Painbytes assessment:  One thumb up for traditional needle acupuncture.  Many studies show benefit, covered by many insurances, safe procedure.  The only caveat is that it doesn’t work the way the acupuncturists think or tell their patients. However there is little evidence ultrasound, tuning forks, etc work.

 

Acupressure-  an old technique of applying pressure over Chinese acupuncture points to provide the same relief as acupuncture to allegedly heal over 50 diseases.  There is an acupressure institute that has paid training courses online and sells several books on acupressure, and is a member of the National Certification Board for Therapeutic Massage and Bodywork.  There is little medical evidence acupressure has all the health benefits it touts.   www.acupressure.com

 

Alexander technique-  A technique developed by Frederick Alexander over a century ago, that is a systemic integration technique.  This is a technique that effectively is a postural alignment technique, used to retrain the body to be more anatomically correct.  It involves “thinking” of balance points.  It is considered experimental by Aetna and some other insurers.   www.alexandertechnique.com

 

AMMA therapy claims to be an extremely specialized form of massage therapy rooted in a philosophy based on Taoism dating back about 5000 years to the period of the legendary Yellow Emperor of China.  Amma therapy combines deep tissue manipulation with the application of pressure, friction, and touch to specific points. While acupuncture inserts needles into the energy pathway to stimulate and move the energy, the Amma therapist relies primarily on the sensitivity and strength of the hands.

www.ammatherapy.net

 

Anti-oxidant function testing (e.g., Spectrox™) is a test for many of the naturally occurring antioxidants in the body including enzymes(superoxidedismutase,catalase,glutathioneperoxidase), essential nutrients (carotenoids, vitamin C, vitamin E, cysteine, selenium) or a wide variety of endogenous compounds (glutathione, sulfhydryl groups, thioredoxin, lipoic acid, coenzyme Q10, urate, bilirubin) or dietary compounds(mannitol,bioflavonoids, phenolicacidderivatives, proanthocyanidins).  Some believe based on almost no valid scientific human studies that replenishing these antioxidants can repair the body in chronic disease.  Mainly chiropractors order these questionable tests that are not covered by Aetna and other insurances.  www.info.spectracell.com

Actra-Rx and Yilishen were adulterated products labeled as “all natural” that contained prescription strength Viagra being sold illegally as “dietary supplements” to treat erectile dysfunction and enhance sexual dysfunction.  They were banned by the FDA after FDA testing demonstrate they illegally contained prescription drugs.  This demonstrates the danger supplements present to the public in that they not only contained prescription drugs being obtained without a prescription but could cause death if given to the wrong person.  Dietary supplements are completely unregulated.

 

Airrosti (Applied Integration for the Rapid Recovery of Soft Tissue Injuries)  This is a commercial company has physical therapy services that state “most patients report immediate relief after the first visit with full resolution after an average of three appointments”.  They tout their program prevents “unnecessary MRIs, pharmaceuticals and surgeries” and most insurance is accepted.  Aetna considers this experimental therapy.   It appears they engage in soft tissue and joint mobilization, with the purpose of improving function and range of motion.  This commercial enterprise has over 150 locations with the vast majority in Texas.  Airrosti (applied integration for the rapid recovery of soft tissue injuries) centers are primarily concentrated in Texas, and focus on management of soft tissue injuries and chronic pain.  Airrosti uses standard physical therapy modalities.  There is a lack of published scientific evidence that Airrosti is superior to other physical therapy providers

Nearly all are chiropractors.    http://www.airrosti.com

 

Anthroposophic medicine-

Anthroposophic medicine- This is an alternative medical system created by Rudolf Steiner (1861-1921) and Ita Wegman (1876-1943) based on Steiner’s spiritual philosophy he called anthroposophy (human wisdom).  This type of medicine is practiced in over 80 countries as a fringe type of medicine, using massage, exercise, counseling, alchemy, eurythmy,and ultra-dilute substances similar to homeopathy.  This type of medicine teaches patient’s past lives influence their illness, and the course of an illness is subject to a “karmic destiny”. Most practitioners are antivaccination.  Generally most of this alternative medicine type has no basis in science and is recognized as ineffective when subjected to scientific controls.  Anthroposophy touted the application of science to spiritual experiences, believing through imagination, inspiration and intuition that inner development could be obtained. Steiner believed in astral bodies.  Steiner believed in human reincarnation and that early humans had clairvoyant capabilities that were lost through excessive reliance on intellectualism. He also believed that all other species devolved from the human species, in exact contrast to Darwin who believed in the evolution of species.  He also believed Lucifer motivated humans in creativity and spirituality and offers the “delusion of divinity”.  The counterpart, Ahriman is the counterpart of Lucifer that tempts humans to deny their link with divinity and embrace a materialistic existence.

The precepts of anthroposophy are embedded in anthroposophic medicine.  There is no alpha or beta level evidence of effectiveness of anthroposophic medicine.  It is largely considered to be quack medicine throughout much of the world.

 

Apitherapy- Apitherapy is the medical use of honey bee products, including bee venom.  Most purported uses remain scientifically unproven including the use of venom for rheumatic diseases and multiple sclerosis.  Many studies are published in foreign journals, are very small, or not randomized.  There is evidence that it is useful in the treatment of burns.  According to the American Apitherapy Society, “Apitherapy is used to treat many illnesses and to alleviate pain from injuries both chronic and acute” to “attain better health through harmony with the bee hive, a true gift of nature”.  http://www.apitherapy.org  However, there is at least one reported death (in 2018) associated with apitherapy, therefore it is not completely harmless.

 

Applied kinesiology (AK)- this is a rather bizarre concept initiated by George Goodheart Jr. a chiropractor that died in 2008 at the age of 90.  He believed every organ dysfunction is accompanied by a specific muscle weakness, that allows diseases to be diagnosed through muscle-testing procedures.  Most often this is used by chiropractors but also naturopaths, dentists, physical therapists, massage therapists, etc.   Note: kinesiology is the study of movement and is a validated physiology construct.  Applied kinesiology on the other hand is a belief system, not grounded in science. The American Cancer Society and American College of Allergy, Asthma, and Immunology stated concerns over the lack of diagnostic validity of applied kinesiology.  Painbytes Assessment: Two thumbs down- the technique does not acknowledge human anatomy or physiology, and diagnostics using this technique has the potential to result in misdiagnosis.  http://en.wikipedia.org/wiki/Applied_kinesiology

 

 

Aromatherapy- Aromatherapy is the use of pure essential oils from fragrant plants (such as peppermint, sweet marjoram, bay, caraway, peppermint, chamomile, and rose) to help relieve health problems and improve the quality of life in general.  The Cochrane collaborative found no consistent evidence of reduction of pain, improvement of sleep, or reduction in clinical depression.  Internal use of most of the essential oils is completely untested for safety.  Slick marketing causes naïve practitioners to believe “therapeutic grade” oils are the only ones that can be used internally, when in reality there is no evidence use of these oils is safe.  The Alliance of International Aromatherapists gives this statement on the internal use of essential oils: “AIA does not endorse internal therapeutic use (oral, vaginal or rectal) of essential oils unless recommended by a health care practitioner trained at an appropriate clinical level. An appropriate level of training must include chemistry, anatomy, diagnostics, physiology, formulation guidelines and safety issues regarding each specific internal route (oral, vaginal or rectal). Please refer to the AIA Safety Guidelines for essential oil use.”  Most practitioners suggesting such oils have not had the requisite training, however in the absence of safety studies, there is no amount of training that can insure safety.  Historical use of these substances internally is also not evidence of proof of safety.  There are a few studies demonstrating capsules of peppermint can improve the pain from inflammatory bowel diseases by altering gut flora but aromatherapists have not put enough time nor effort into proving the safety or efficacy of their therapies. There are several essential oils that should not be taken internally due to risks of liver damage include buchu, cassia, aniseed, basil, bay, clove, fennel, and tarragon. Other essential oils that may cause toxicity taken internally include camphor, mugwort, nightshade, pennyroyal, rue, savin, southernwood, stinging nettles, tansy, thuja, wintergreen, wormseed, and wormwood.  Painbytes assessment: one thumb down- no evidence of efficacy for pain but no real harms shown from topical use.  There are some oils that are consumed internally and this is potentially overtly dangerous. Finally, a 21st century use of “aromatherapy” especially offered as “relaxation”  is a code word for some sex trade offerings. http://www.cochrane.org/CD003150/DEMENTIA_aromatherapy-for-promotion-of-relaxation-and-sleep-relief-of-pain-and-reduction-of-depressive-symptoms-in-dementia

https://www.naha.org

 

Art therapy-  Is not covered by many insurances, but is a legitimate form of complementary therapy with a university masters degree or higher, and there is a board certification process.  Art therapy is an effective means to help with adolescents and younger in diagnosis and to help with therapy.  Depression and behavioral issues can be addressed by art therapy but pain per se is not addressed by art therapy.  Painbytes assessment: neutral.  It is a university based program of study but there are not enough studies to support the use in pain management.  Depression treatment may be treated with this therapy.    http://www.arttherapy.org 

 

Aura healing- is an alternative medicine energy based therapy.  The energy healer uses the patient’s energy field to help the patient breaks free from the afflictions of the body, mind, and spirit.  It is also known as spiritual healing, energy healing, or psychic healing.  The aura healers believe many physical problems have their root cause on an energy level.  After grounding themselves to become “present as spirit in the body” via meditation, the healer combs through the patient aura to support the patient in releasing “foreign energy” and psychic debris.  The healer then helps the patient increases the “flow of earth, cosmic, life-force, healing, and creating energies”.  Aura healings can be done remotely or even over the phone.  Generally most Western medicine considers Aura healing to be quack therapy.  There is no evidence aura healing is anything more than a mind game.  Painbytes assessment: two thumbs down

 

Auricular Therapy- (Auriculotherapy)-  A type of acupuncture of the ear soft tissues based on placing needles into the cartilage of the ear (auricular acupuncture) or use of pressure over soft tissues of the ear (auricular acupressure) or use of a laser on the soft tissues of the ears (laser auriculotherapy) or use of electroacupuncture stimulation (EAS) in order to achieve the effect desired.  Unlike traditional acupuncture, the auricular acupuncture needles or applied pressure via magnets or stones may be left in the ear for up to a month.  The modern origins of this alternative medicine therapy was with the French neurologist Paul Nogler, a French neurologist, who in 1957 published a “map of the ear” partially based on his observations and partially on the Chinese art of auriculotherapy extending back thousands of years.   

A systematic review and meta-analysis of auricular therapy for pain management (Evid Based Compl. Alt. Med 8/14 by Yeh CH, et al) found auricular therapy provided significant pain relief compared to sham or control groups however the analysis is questionable since it included many poorly conducted studies that would not meet the criteria for highest scientific trial design. He also found based on this analysis that auricular acupressure boasts the largest strength of evidence for pain relief followed by auricular acupuncture and that electroacupuncture was not found to be effective for pain.  Auricular acupuncture was found not to be any more effective in smoking cessation than sham therapy (J. Chinese Med Assoc 70(8), Aug 2007, 331-8).  Acupuncture of the ear for cancer showed less effectiveness than conventional analgesics in a randomized trial (J Tradit Chin Med 18(1):31-8, 1998).  Acupressure of the ear was found to not have any significant improvement over sham therapy in average low back pain intensity, back pain disability, or quality of life in those with chronic low back pain (Evid Based Complementary and Alternative Medicine 2013/196978)

PAINBYTES ASSESSMENT: Neutral:  There are mixed results from the studies, little science behind the treatment and potential damage from misdiagnosis by auricular diagnosis.

 

Autogenous lymphocytic factor

 

Auto urine therapy – is literally using  one’s own urine, internally or externally, for health benefits and preventative health maintenance.  It has been claimed to be helpful in a number of illnesses including the common cold, sore throat, asthma, itching, psoriasis, eczema, and skin cancer.   In one article, it is claimed “urine should be sipped like tea and not drunk like water”.  “Urine passed during the night before 3 AM should not be used” and the “quantity used is left up to the individual”.  There is not much clinic evidence this therapy would help with anything but it does represent one of the more unorthodox therapies, even for alternative therapies.  Painbytes assessment: two thumbs down- little evidence it is useful for pain management and the potential for harm exists.

http://www.vanderbilt.edu/AnS/psychology/health_psychology/Urine_Therapy.htm

Ayurvedic Therapy-  Practiced in India for more than 5000 years, Ayurvedic tradition holds that illness is a state of imbalance among body systems that can be detected through diagnostic procedures such as reading the pulse and observing the tongue. The use of a multitude of therapies are used including enemas, purgation, modified fasting, dietary advice, lifestyle advice, manual treatments, phytotherapy, yoga, meditation, and music/mantra are used as treatments to address nearly all diseases treated by western medicine. Human clinical trials for osteoarthritis show large clinical and statistical effects for the medication Rumalaya compound and to a lesser degree Shunti-Guduchi are useful. (Rheumatol Int 2015 Feb:35(2) 211-32.  There is some evidence Bacopa monnieri has strong antidepressant effects and pain killing effects.  It utilizes the Cox-2 inhibitory mechanism (same as Celebrex) and augments morphine analgesia, opioid induced hyperalgesia, and is a moderately powerful pain medication. (Curr Med Chem 2013;20(8):1028-37).    Other anti-inflammatory and pain killer meds include Adiantum capillus veneris Linn and Mesua ferrea Linn (Cobra’s saffron).   Polyherb therapy for rheumatoid arthritis has been demonstrated with Tinospora cordifolia and Zingiber officinale (Clin Rheumatol 2012 Feb;31(2):259-269).  There is animal model evidence of the analgesic and hypnotic effect of Laghupanchamula in rats (Ayu. 2014 Jan;35(1):79-84).  There are safety concerns with this medication as there have been reports of lead poisoning with Ayurvedic medications given that they are not assayed for safety (J Gen Intern Med 2012 Oct;27(10):1384-6,  J Hematol Oncol 2011 Dec 20;4:51,   Acta Clin Belg 2008 Jan-Feb;63(1):42-45,  N Z Med J 2006 May 5:119(1233):U1958,  Ned Tijdschr Geneeskd 2005 Dec 24:149(52);2893-6,   Med Klin (Munich) 2004 Aug 15;99(8);476-80

Painbytes assessment: neutral: safety concerns of lead poisoning are real however, there are several well constructed studies demonstrate effectiveness.

Bach flower therapy- this therapy was devised by “Doctor” Edward Bach, a homeopath, who devised a system of treatment of emotions with 38 flower essences.  Flower essences are prepared by a sun method involving floating the flower heads in pure water for three hours in direct sunlight or boiling the woodier plants and those that bloom when the sun is weak.  Once the “energy of the flowers has transferred to the water, the energized water is mixed with an equal quantity of brandy”.  This becomes the “mother tincture” that is further diluted into brandy at a rate of two drops of mother tincture to 30ml of brandy to make the stock bottles seen in shops.  These “flower essences” are paired with a Bach list of remedies- for instance Aspen is used to treat the “fear of unknown things”, Cherry Plum is used to treat the “fear of the mind giving way”, Chicory for “selfish, possessive love”, Clematis for “dreaming of the future without working in the present”, Gorse for “hopelessness and despair”, Holly for “hatred, envy and jealousy” and so on.  The Bach center in Mt Vernon offers courses in the system including becoming a practitioner, becoming a licensed trainer, Level 1-3 courses, and courses on “How to Build Your Business” in Bach therapy.  Since Bach was a homeopath, there is no alpha or beta scientific evidence any of these treatments, consisting mainly of alcohol, actually work.  There are some delta level uncontrolled trials  (eg. I gave then flower therapy and they got better) such as a Spanish publication “Emotional support and Bach Flower Therapy (Rev Enferm 2009 Oct;32(10):16-9) and a non abstracted opinion on the use of the therapy in the treatment of chronic major depressive disorder (Altern Ther Health Med 2003 Nov-Dec;9(6):112, 108-10.)   Recommendation- avoid due to the lack of scientific evidence and the mercenary nature of marketing this alcoholic product.

Balneotherapy- the treatment of disease by bathing or immersion in mineral water or mineral-containing mud, a traditional medicine technique practiced at spas, and part of several traditional folk medicine treatments.  Balneotherapy may involve hot or cold water, massage through moving water, relaxation, or stimulation.  It is distinct from hydrotherapy, but there are some overlaps.  Balneotherapy has been used to treat many diseases including arthritis, fibromyalgia and for relaxation.  Another type of balneotherapy uses medicinal clays and is known as fangotherpy.  There is one quality RCT showing balneotherapy was superior to paroxetine (Paxil) for generalized anxiety disorder (Adv Ther 2018 Mar 5. Doi: 10.1007/s12325-018-0680-6).    There is some alpha level evidence of effectiveness.

      There are mixed results on cortisol levels with balneotherapy (Int J Biometerol 2018 Feb 18:doi:10.0007/s00484-018-1504-8).  Baleotherapy is clinically effective in relieving pain and stiffness in osteoarthritis of the knee, and improving function in a meta-analysis (Clin Rheumatol 2017 Aug;36(8):1839-47).   There is insufficient evidence to recommend balneotherapy for the treatment of rheumatoid arthritis (Eur J Phys Rehabil Med 2015 Dec;51(6):833-47).  For fibromyalgia syndrome, balneotherapy results in a small reduction in pain and large quantity of improvement of Quality of life) (Arthritis Res Ther, 2014 Jul7;R 141).  Balneotherapy results in an improvement short term for knee osteoarthritis (Clin Rheumatol 2009 May;28(5):501-7)

 

Bee sting therapy- see apitherapy

Biodanza- a Spanish neologism meaning life-dance.  This is a system of self-development, using music, movement, and positive thoughts to deepen self awareness, and thereby promotes the ability to make a “holistic link to oneself and one’s emotions and express them”.   Biodanza is the Hispanic equivalent to Tai Chi, but with more movement.  There are schools of Biodanza in San Francisco and LA.  Biodanza has 4 “lines” of vivencia (living in the present moment): vitality, sexuality, creativity, and affectivity.  Additionally there is transcendence, which means connecting to something greater in the universe.  There are some studies on biodanza, a delta level study showing biodanza reduces acute pain severity by 16%  in women with fibromyalgia (Pain Manag Nurs 2017 Oct;18(5):319-27).  There is a biodanza beta level RCT demonstrating significant reduction of stress and depression in university students (J Altern Complement Med 2017 Jul;23(7):558-565).  However there was also a gamma level fibromyalgia study that found biodanza inferior to multidisciplinary therapy (Acta Reumatol Port 2012 Jul-Sep;37(3):240-50).  Lastly, there was a RCT for fibromyalgia (beta level) that was invalid due to a high dropout rate using aqua-biodanza for treatment of fibromyalgia. (Aten Primaria 2012 Nov;44(11):641-9)

 

Bioenergetic therapy – is a form of body psychotherapy developed by Alexander Lowen and John Pierrakos, students of William Reich.  The idea behind this treatment is that blocks to emotional expression and wellness are expressed in the body as chronic muscle tensions that are often subconscious.  The blocks are treated by combining bioenergetically designed physical exercises, affective expressions, and palpation of the muscular tensions.   The therapist “reads the body of the patient, resonates with its energy, feels the emotions, listens, hears and answers the words. This therapy is supposedly used in sexual healing.   There is no scientific evidence of efficacy.   Painbytes assessment: all energy healing therapies have no basis in science, have no proof of efficacy, and using such systems to diagnose and direct therapies are dangerous since they delay or misdiagnose disease.  Two thumbs down.

http://www.bioenergetic-therapy.com/index.php/en/

 

Biofeedback: A medical technique used especially for stress-related conditions, such as asthma, migraines, insomnia, and high blood pressure, biofeedback is a way of monitoring minute metabolic changes in one's own body (for example, temperature changes, heart rate, and muscle tension) with the aid of sensitive machines. By consciously visualizing, relaxing, or imagining while observing light, sound, or metered feedback, the client learns to make subtle adjustments to move toward a more balanced internal state.

 

Biomagnetic pair- is also called “medical biomagnetism” and is touted as a “natural therapy that purposes diagnosing and treating a large number of illnesses throuth the use of pairs of magnets of medium intensity that seek to equalize the organism’s pH level.”  This is another bizarre concept that has no foundation in science since the pH of an organism is completely independent of magnetic or energy fields.  It is claimed “a large number of illnesses, including cancer and many other complex diseases, are associated with fundamental alterations in the pH level in the internal organs and with the presence of viruses, bacteria, fungus, parasites, toxins, and other harmful factors.  The development of illness cannot happen with a balanced pH level.”  The claims are that unlike magnet therapy, the Biomagnetic Pair uses pairs of magnets of opposite charges to depolarize areas in the body that are unbalanced due to pathogens or other factors that resonate energetically and vibrationally.  They also claim the biomagnetic pair can diagnose the etiology and combat the real causes of the diseases, especially viruses, even before symptoms of disease occurs.  The system, developed by a Mexican doctor, uses 350 different biomagnetic pairs that cover most of the glandular dysfunctions, diseases, emotional issues, syndromes, and illnesses. 

There is no science, no validated studies, and little logic in this therapy.

Painbytes assessment: Two thumbs down.

http://biomagnetism.net/biomagneticpair/

 

Biomagnetic therapy- see biomagnetic pair

Bioresonance therapy- see biomagnetic pair

 

Bovine cartilage products-  aka Antitumor Angiogenesis Factor (anti-TAF), Bovine Tracheal Cartilage (BTC), Cartilage Trachéal de Bovins, Cartílago Bovino, Catrix, Catrix-S, Collagen Bovine, Collagène Bovin, Glycosaminoglycan Polysulphuric Acid Complex, Processed Bovine Cartilage, Psoriacin, Psoriacin-T, Rumalon.  These are cow derived cartilage used to treat a variety of diseases.  The theory behind their use is that they contain chondroitin and glucosamine- two building blocks of cartilage.  Some of these products (supplements) are very expensive, especially in combination with other components.  There are no significant quality studies linking bovine cartilage to significant improvements in disease.  It is possibly effective in treating poison oak and ivy, treating acne, skin psoriasis, hemorrhoids and anal itching, rheumatoid arthritis, dry socket after tooth extraction.   It may be effective in some cases of osteoarthritis.  But overall, it is very questionable.  Aetna considers it experimental.

http://www.medicinenet.com/bovine_cartilage/supplements-vitamins.htm

 

Cao Gio- also known as "coin rubbing" or "coining", is practiced throughout Southeast Asia (esp. Vietnam and Thailand) and by immigrants from such areas to the US and other countries.  Literally, "Cao Gio" means catch the wind.  In the Southeastern Asia belief, the "wind" is a "body force" or humor that is  imbalanced. An excess of "wind" in the body can be released by pulling the "wind" to the surface of the body, creating a pathway in which it can be released.  Cao Gio uses a coin to create abrasion lines of the skin, extending from the spine outwards along the path of the ribs.  The body is first treated with an oil (eucalyptus, peppermint, cinnamon, winter green, menthol, camphor) or ointment or balm (such as Tiger Balm), then the edge of a coin makes linear red abrasions of the skin over and over again .  The amount of "wind" is measured by the degree of redness appearing on the body after coining, that also measures the severity of the illness.  If the red marks are mild, then the underlying illness is mild.  If the marks are severely red, then there is much "excess wind" and the disease is major. The long red marks on the back (up to 20) fade after a few days.  Cao Gio is used to treat a variety of illnesses such as aches, pains, fevers, colds, cough, nausea, abdominal pain, chills and symptoms related to changes in the weather.  

     Levels of evidence: There is no alpha, beta, gamma, or delta evidence of effectiveness.  

Also see gua sha, a closely related technique used in China and Korea, except a sharpened object is used to create the dermabrasion rather than a coin. 

Cellular therapy – This is not the same as human stem cell therapy.   It is instead a treatment with animal cells, also called live cell therapy, cellular suspensions, glandular therapy, fresh cell therapy, siccacell therapy, embryonic cell therapy, and organotherapy -- refers to various procedures in which processed tissue from animal embryos, fetuses or organs, is injected or taken orally. Products are obtained from specific organs or tissues said to correspond with the unhealthy organs or tissues of the recipient. Proponents claim that the recipient's body automatically transports the injected cells to the target organs, where they supposedly strengthen them and regenerate their structure. The organs and glands used in cell treatment include brain, pituitary, thyroid, adrenals, thymus, liver, kidney, pancreas, spleen, heart, ovary, testis, and parotid. Several different types of cell or cell extract can be given simultaneously -- some practitioners routinely give up to 20 or more at once.  The treatment is dangerous and has resulted in many deaths and serious immunological reactions.  It is not only experimental but is overtly hazardous and should be avoided. It is sometimes promoted in the US by Naturopaths, a sort of alternative medical system doctor that has not gone to medical school.  The original use of cellular therapy was in 1912 when German physicians attempted to treat hypothyroid children with thyroid cells.  Paul Niehans MD, a Swiss physician was known as the “father of cell therapy”.  The clinic he developed in Clarens-Montreaux Switzerland continues to attract patients at the tune of $10,000 per week.  John Brinkly MD began doing operations implanting men with tissue from goat testicles in 1917 and by 1941 had his license to practice revoked due to quackery.  The technique was used in Tijuana Mexico where clinics continue, since 1970.  Unwitting patients will travel there to “build the immune system” and “help patients” with Down’s syndrome, Alzheimer’s disease, epilepsy, AIDS, and various other diseases.  Of course there are no scientific studies of significance to support the use of this bizarre therapy.

Painbytes assessment: Two thumbs down.   Experimental, no data on safety or efficacy, shady practices.

 

Chakra Healing- Chakra healing is an energy field therapy that uses the concept of the 7 major chakras or energy centers, that are located in the midline from above the head to below the pelvis.  They are defined as the “openings for life energy to flow into and out of our aura. Their function is to vitalize the physical body and to bring about the development of our self-consciousness. They are associated with our physical, mental and emotional interactions. “  They are invisible but “can be perceived intuitively by trained energy workers.” The energy workers claim to be able to determine which chakras are functioning properly and which are working overtime.  The theory is that if some of the chakras are performing at a reduced level, the others have to pick up the slack, leading to a “blowout” of a healthy chakra. There is little proof there is any validity to the technique, a paucity of studies that are of low quality, and many “case studies” subject to bias.  Chakra healing for pain has not been demonstrated by scientific standards to be effective.

Painbytes assessment: energy therapies are largely quackery since there is no scientific proof they work.  Should be avoided.  Two thumbs down. 

 

Chelation therapy: Typically administered in an osteopathic or medical doctor's office, chelation therapy is a series of intravenous injections of the synthetic amino acid ethylenediaminetetraacetic acid, designed to detoxify the body of heavy metals. While the treatment often is used to treat arteriosclerosis, or hardening of the arteries with little evidence of effectiveness.  However in recent times, chelation has been used as a treatment for fibromyalgia in a series of 20-30 treatments over several months.  These are expensive treatments, costing thousands of dollars for the series, usually are offered by doctors preying on the desperation of those with fibromyalgia, but with no scientific evidence of effectiveness.  The treatment can also be hazardous due to removal of essential elements of the body.

Painbytes Assessment:  Two thumbs down

Chinese Pulse Diagnosis-  In Traditional Chinese Medicine (TCM) , before acupuncture, herbs and massage are prescribed, a diagnosis is made from evaluation of the pulse and examination of the tongue.  Pulse diagnosis is not at all similar to evaluation of pulse in modern medicine, instead is a perception of energies flowing through the body and any obstruction to such flow. From the work of Stephen Barrett, MD it can be seen the diagnosis and therapy prescribed varies wildly from one TCM practitioner to the next, even when they have years of training. 

"Researchers who examined 16 TCM acupuncture texts or treatment articles to determine the consistency of diagnosis and recommended treatment for chronic low-back pain. Although 24 diagnostic patterns were described by one or more texts, only 4 patterns were described by at least half of them. Most texts (12/16) described only 3 or 4 patterns. The patterns could be categorized into 3 broad types:

  1. Cold, damp, wind, heat channel obstruction patterns

  2. Kidney vacuity patterns (sometimes differentiated into yang and yin patterns)

  3. blood (or blood and qi) stasis patterns.

Several acupuncture points were recommended by most texts regardless of the diagnosis, whereas other acupoints were recommended for specific diagnostic patterns. There was, however, substantial variation between texts in recommended acupoints, with fewer than 20% of all acupoints recommended by half or more of the texts [1].

In a study published in 2001, a 40-year-old woman with chronic back pain who visited seven acupuncturists during a 2-week period was diagnosed with "Qi stagnation" by 6 of them, "blood stagnation" by 5 , "kidney Qi deficiency" by 2, "yin deficiency" by 1, and "liver Qi deficiency" by 1. The proposed treatments varied even more. Among the six who recorded their recommendations, the practitioners planned to use between 7 and 26 needles inserted into 4 to 16 specific "acupuncture points" in the back, leg, hand, and foot. Of 28 acupuncture points selected, only 4 (14%) were prescribed by two or more acupuncturists. [2]. The study appears to have been designed to make the results as consistent as possible. All of the acupuncturists had been trained at a school of traditional Chinese medicine (TCM). Six other volunteers were excluded because they "used highly atypical practices," and three were excluded because they had been in practice for less than three years. The study's authors stated that the diagnostic findings showed "considerable consistency" because nearly all of the practitioners found Qi or blood stagnation. However, the most likely explanation was that these are diagnosed in nearly everyone.

In another study, six TCM acupuncturists evaluated the same six patients on the same day. Twenty diagnoses and 65 acupoints were used at least once. The diagnosis of "Qi/Blood Stagnation with Kidney Deficiency" and the acupoint UB23 were used for every patient by most acupuncturists. However, consistency across acupuncturists regarding diagnostic details and other acupoints was poor. No diagnoses, and only one acupoint, were used preferentially for a subgroup of patients. Some diagnoses and treatment recommendations were dependent more on the practitioner than on the patient. Fine-grained diagnoses and most acupoints were unrelated to either patient or practitioner. The researchers concluded that TCM diagnoses and treatment recommendations for specific patients with chronic low back pain vary widely from one practitioner to another [3].

Another study examined TCM diagnoses and treatments for patients with chronic low-back pain using two separate sets of treatment records. Information from more than 150 initial visits was available for analysis. A diagnosis of "Qi and Blood Stagnation" or "Qi Stagnation" was made for 85% of patients. A diagnosis of kidney deficiency (or one of its three subtypes) was made for 33%-51% of patients. Other specific diagnoses were made for less than 20% of the patients. An average of 12-13 needles was used in each treatment. Although more than 85 different acupoints were used in each data set, only 5 or 6 acupoints were used in more than 20 of the treatments in each data set. Only two of those acupoints (UB23, UB40) were the same for both sources of data. More than half of the patients received adjunctive treatments, including heat (36%-67%), and cupping (16%-21%). There was substantial variability in treatments among providers [4].

In a larger study published in 2004, three TCM practitioners examined the same 39 rheumatoid arthritis (RA) patients separately at the University of Maryland General Clinical Research Center. Each patient filled out a questionnaire and underwent a physical examination that included tongue and pulse diagnosis. Then each practitioner provided both a TCM diagnosis and a herbal prescription. Agreement on TCM diagnoses among the 3 pairs of TCM practitioners ranged from 25.6% to 33.3%. The degree to which the herbal prescriptions agreed with textbook recommended practice of each TCM diagnosis ranged from 87.2% to 100%. The study's authors concluded:

The total agreement on TCM diagnosis on RA patients among 3 TCM practitioners was low. When less stringent, but theoretically justifiable, criteria were employed, greater consensus was obtained. . . . The correspondence between the TCM diagnosis and the herbal formula prescribed for that diagnosis was high, although there was little agreement among the 3 practitioners with respect to the herbal formulas prescribed for individual patients [5].

The University of Maryland researchers then repeated the above study using 40 RA patients and three practitioners who had had at least five years of experience. The results were nearly identical to the previous findings [6]."  Therefore pulse diagnosis not only results in significant disagreement, but the applied use of therapies also varies wildly, bringing into question both the diagnostic consistency of pulse diagnosis and the therapies used. 

Ref. 1. Alternative and Complementary Medicine 5:4150425, 1999.  2. Southern Medical Journal 94:486-492, 2001  3. Complementary Therapies in Medicine 9:154-166, 2001.  4. Alternative and Complementary Medicine 7:641-650, 2001.  5. Alternative Therapies in Health and Medicine 10:58-63, 2004  6. Alternative Therapies in Health and Medicine 11:415-421, 2005.

 

 

Chios Energy Healing- is an energy healing method that uses a trademarked term “Chios”, that is actually a type of what is claimed to be a unique approach to using both the aura and chakra’s (see Chakra healing above) for healing…  They claim Reiki and other energy healing forms do not translate to Chios energy healing.  The system can be learned by anyone but is taught by “Chios Master Teachers” and is learned in part by a Chios book sold on Amazon.  The system awards symbols for each level achieved and a secret symbol for master teachers.   The system teaches to reach the hands in front of the patient and feel the auras, diagnosing what is wrong with them, use symbols for treatment, and imagining bringing energy into the hands.  The practitioners are taught to imagine layers of energy and light near the patient, and see the colors of the auras.  The practitioners are taught to charge the chakras with the hands placed on the body with the right palm over the imagined chakra and the left hand on the back of the right, moving the hands away then apart, then sending colors to the chakra by moving the hands in circles.  The psychic senses are emphasized in receiving and transmitting energy.

There is no scientific study demonstrating effectiveness of Chios….it is a belief system rather than scientifically validated system.  Painbytes assessment: Two thumbs down.  www.chioshealing.com

 

Chiropractic- Chiropractic is a alternative medical system based on the premise that the spine is literally the backbone of human health: misalignments of the vertebrae caused by poor posture or trauma result in pressure on the spinal cord, which may lead to diminished function and illness. Chiropractic was started by Daniel David Palmer, involved in several “natural healing philosophies” such as animal magnetism, vitalism, spiritualism, and others, when in 1895 he manipulated the spine of a man who had lost his hearing earlier when he twisted his back, hearing a pop.  Palmer ostensibly restored the hearing by manipulation, and on this basis alone, developed chiropractic. He opened a school in 1897 of chiropractic. There were many similarities of chiropractic and Palmer’s writings to that of Still’s creation of osteopathy a decade earlier. 

The chiropractor seeks to analyze and correct spinal misalignments through spinal manipulation or adjustment.  At best, chiropractors offer counseling, massage, electrotherapy, manipulation of the spine and other joints, and supplements for back and neck pain.  At worst, chiropractors claim to be primary care physicians, neurologists, etc. and fraudulently claim to be able to treat everything the modern medical system can treat.  There is a wide array of practitioners in between.  Chiropractic is not without risk: risk of misdiagnosis of serious medical problems as spine misalignment, delay in diagnosis of the treatment of cancer and other aggressive diseases they may treat with supplements and manipulation, and dangers of manipulation itself with numerous reports of permanent paralysis and injury due to manipulation of the neck.  Adverse events are reported in 38% of chiropractic studies (Spine J 2016 Sep;16(9);1143-51).  Lumbar manipulation may result in cauda equina syndrome (paralysis), disc herniation, fractures, hematomas, and other neurological or vascular compromise, soft tissue trauma, muscle abscesses, disruption of fracture healing and esophageal rupture (J Manipulative Physiol Ther 2015 Nov-Dec;38(9):677-91).

Alpha level evidence:

Lack of evidence to support chiropractic for adolescent idiopathic scoliosis (J Manipulative Physiol Ther 2017 Jul-Aug;40(6):452-458.  In cervical manipulation, there is a large effect size on increasing range of motion of the neck and mouth opening, and in patients with tennis elbow, after cervical manipulation there is a significant increase in pain free handgrip strength (J Altern Complement Med 2017 Sep;23(9):667-675). A review found chiropractic controls in trials are very imperfect, and few trials assess for successful blinding of controls or active, thereby introducing significant bias in chiropractic studies (Spine J 2017 Mar;17(3):445-456).  A review found adding chiropractic to medical therapy offers no additional benefit in the treatment of acute low back pain (Am J Emerg Med 2017 Jan; 35(1):55-61).  European guidelines recommend chiropractic for acute lumbar disc herniation or for acute low back pain (Eur J Pain 2017 Feb;21(2):201-216) however compared to other therapies, chiropractic offers no difference in effectiveness  and is no better than usual medical treatments (Cochrane Database Syst Rev 2012 Sep 12;(9):CD008880).  There is evidence of chiropractic benefit in neck pain, shoulder pain and sport injuries, but there is no conclusive scientific evidence to recommend chiropractic for treatment of asthma, infant colic, autism spectrum disorder, gastrointestinal problems, fibromyalgia, chronic back pain, and carpal tunnel syndrome (Int J Community Based Nurs Midwifery 2015 Oct;3(4):244-54).

 

Chung Moo Doe therapy- The word chung means true or correct with the abstract meanings of mental or mind.  Moo is Chinese for military with the abstract meanings physical or body.  Doe is Chinese for road, way, path, truth. This therapy is a combination of 8 martial arts and is more a body therapy than mind therapy, but encompasses both.  It emphasizes correct breathing with Qi Gong breathing, Tai Chi movements, Tae Kwon Do, Samurai, Ju Jitsu, Kung Fu, Ship Pal Gae, Bagwa.  Since several of these martial arts have been demonstrated to improve flexibility and improve pain, the Chung Moo Doe therapy would be expected to also improve chronic pain.  There are no specific studies for the combined therapies effect however.   Painbytes assessment: neutral given the lack of any specific studies but given that each component has movement therapies that could be useful.

http://www.oomyungdoe-ne.com/

Coining- see cao gio

Colloidal Silver- Colloidal silver is an illegal drug in the US (not a supplement), sold via the internet and in some vitamin stores as primarily a "natural" method of treating infections as a substitute for antibiotics.  Although it has been used for 120 years, there is nearly no medical or scientific evidence of effectiveness or safety, yet it is widely used.  It has a nasty side effect of turning the skin, whites of the eyes, and fingernail beds a grey to bluish color (called argyria) due to deposits of silver in these areas, making the person appear to be near death.  Whacko internet doctors and naturopaths, who do not value human safety or believe it is necessary to prove effectiveness, tout this misbranded drug as a panacea for bacterial, viral, fungal infections and as an anti-inflammatory agent.  

     Evidence of safety and effectiveness:  In 1999 the FDA issued a ruling colloidal silver or silver salts for human consumption is a misbranded drug, and is neither safe nor effective.  This means it is not a supplement, but is an illegally produced drug in the US, and cannot be sold legally via the internet or in stores (Fed Regist. 1999 Aug 17;64(158):44653-8).  There are no alpha or beta level studies to support its use. There is a beta level study showing that colloidal silver applied topically was completely ineffective in treatment of rhinosinusitis (J Otolaryngol Head Neck Surg. 2017 Nov 25;46(1):64).  A delta (low) level report showed healing of superficial ulcers with a colloidal silver spray (Panminerva Med. 2011 Sep;53(3):185-91).  There is a epsilon level (very low) single case report of treatment of a child with cystic fibrosis with colloidal silver (J R Soc Med. 2008 Jul;101 Suppl 1:S51-2.).  There is a case report of kidney damage from colloidal silver treatment for lymphoma (BMC Nephrol. 2016 May 17;17(1):49) and another with nephrotic syndrome associated with colloidal silver (Med Monatsschr Pharm. 2008 Feb;31(2):67-9).  Also there is a case report of a woman admitted to the hospital for acute psychosis after long term colloidal silver ingestion (Ann Clin Biochem. 2012 May;49(Pt 3):300-1).  A case report exists of a man presenting with seizures and brain degeneration after long term use of ingested colloidal silver (Ann Clin Biochem. 2009 Nov;46(Pt 6):520-2.) and another associated with seizures (Neurology. 2004 Apr 27;62(8):1408-10).  In a review of colloidal silver effects it was stated: "Consumption of large doses of colloidal silver can result in coma, pleural edema, and hemolysis. Colloidal silver is also toxic to the bone marrow and may be associated with agranulocytosis. The toxic effects of inorganic silver ingested orally in large doses are very similar to any corrosive solution. Such ingestion can result in burning of the throat and epigastrium, leading to abdominal pain, vomiting, and diarrhea. The patient often suffers convulsions and goes into shock." (Dermatol Online J. 2005 Mar 1;11(1):12) 

Colonic irrigation (colonic cleansing, colonic lavage)- This treatment has been used to treat back pain based on the unsubstantiated supposition that “weakness in the intestine causes weakness of the back and makes it prone to injury” and that “the muscles of the back have nerve pathway connections to the large intestines”.   This is simply nonsense spouted by those trying to make a fast buck off of colon cleansing.  Colonic irrigation is approved by the FDA to clear the colon before surgery or for radiology exams, but not for the purposes touted for “detoxifying”.  In fact,  Dr. Ranit Mishiori published an excellent paper in the Journal of Family Practice that colon cleanses don’t do much except cause uncomfortable side effects such as severe cramping, and in some cases dangerous side effects due to perforation of the colon and introduction of bacteria.  Colonic irrigation was shown as far back as 1919 to be a scam but was reintroduced by spas seeking clients for money in the 1990s.  The reduction in bacteria due to colonic irrigation can be hazardous to the body since we need bacteria in the gut to ease digestion and voiding of waste.  Now nurses, believing having stool residing in the bowel is bad for the body (completely nonsensical) offer colonic therapy as a voodoo for those with anal fixations.

Painbytes Assessment: Two Thumbs down.  Insufficient proven benefit and certainly no scientifically validated studies for pain reduction. Has significant potential for harm.

 

 

Color therapy or Chromotherapy-  This alternative medicine therapy is classified by its practitioners as a “vibrational therapy” because color is produced by electromagnetic waves.  Typically the therapy conflates feelings about color with the ability to employ color as therapy.   Color therapy may use gemstones, candles, lamps, crystal wands, crystal and glass prisms, colored fabrics, color bath treatments, colored eye lenses, and lasers.  These are used to balance the aura fields and the physical, emotional, spiritual, or mental energies. 

Painbytes Assessment: Two thumbs down.  No scientific basis- this is a belief system rather than a medical treatment.

 

Conceptual mind-body techniques- These are a series of techniques that involve the use of the physical plus mental techniques that are touted to help with chronic pain.   These include Emotional Freedom Techniques (EFT), being a form of psychological acupressure.  Tapping specific meridians on the head and chest with the fingertips is used to “transfer kinetic energy” while you think about your problems and vocalize positive affirmations.  Theoretically this works to clear the “short circuit” or emotional block, from the body’s bioenergy system, thus restoring body’s balance that essential for optimal health and physical disease healing.  

Painbytes Assessment: Neutral- no scientific evidence of effectiveness for pain, use of unproven meridians, but the meditation aspect could have positive benefits.

 

Craniosacral therapy (CST)- this alternative body-mind therapy originated with cranial osteopathy, developed by an osteopath William Sutherland, who noted the cranial sutures looked like gills of a fish and proposed they move with respiration.  John Upledger conducted the purported pulse of the cranial bone movement and developed the concept of a cranial rhythm.  Their research findings were later concluded to not meet scientific standards of proof of effectiveness of the CST and cranial bone movement.  Current practitioners believe small rhythmic motions of the cranial bones occur due to the cerebral spinal fluid or arterial pulsations and they can detect these movements by palpating the cranium and the sacrum, focusing intently on the patient’s body, becoming “in tune” with the patient’s body, calling this process “Entrainment”.  Patients do report relaxation during the process.  The sacrum, that has been shown scientifically to have such small movements that are not reliably determinable, is palpated in a similar fashion to attempt to detect small movements.  CST is effective for relaxation, but has not been demonstrated to be of any other value in scientific studies.  The studies that were conducted was so poorly designed that they could not be used to draw any conclusions.  The science behind CST is extremely questionable with very little evidence suggesting cranial sutures move at all and the sacroiliac joint motions so subtle that different practitioners do not agree on such movement.   Painbytes assessment:  one thumb down due to erroneous dianostics leading to misdiagnosis or delay in diagnosis.  It is useful for relaxation but nothing else.  The science is bad and buying into this therapy is a belief system rather than proven medical science.  The placebo effect is probably strong, both for patient and practitioner.

 

Crystal healing- is an “energy healing” alternative therapy that believes crystals (especially quartz) and stones have healing powers.  The crystals are either aligned with the chakras of the body (see description above) in an attempt to construct an “energy grid” that surrounds the client with healing energy.  There is no available scientific evidence that shows the presence of chakras, energy fields, or healing from crystals.  The crystals are therefore a shtick or prop employed by alternative healers to induce an air mysticism about the technique for the unknowing clients.  Painbytes recommendation:  avoid.  Two thumbs down.

 

Cupping- This alternative therapy has been practiced for over 3,000 years and is performed frequently in Muslim countries as a treatment for anemia, hemophilia, rheumatic diseases, back pain, fertility disorders, and skin disorders.  It has almost no scientific study backing its use, but is a traditional medicine method that uses closed cups or bowls with a vacuum inside, placed on the skin to suck part of the soft tissues inward, breaking the capillaries at the point of contact with the skin. 

   Dry cupping involves the use of cups 1-3 inches wide made of plastic or glass in modern times.  There are two types of dry cupping: fire cupping and vacuum cupping.  Fire cupping involves suction created by heating the cup or air inside with an open flame or a bath in hot scented oils or an using alcohol soaked cotton ball that is set on fire in the cup heating the interior.  In fire cupping, the fires is extinguished, then then the cup is placed against the skin.  As the air inside cools, a suction is created, holding the cups onto the skin.  Vacuum cupping is the other type of dry cupping that uses rubber cups used to squeeze out the air inside or vacuum cups that have a one way evacuation valve or evacuation tube connected to a suction device.  The skin may be lubricated and the cups may slowly move across the skin on their own.         Wet cupping (also called Hijama) is used primarily in Muslim countries.  It involves making several small incisions in the skin, then placing the fire cupping over the incised area.  This sucks blood from the wounds and partially fills the cups with blood.  This is neither safe or effective, and strongly resembles the bleeding procedures used in the 1600s and 1700s in Europe that weakens and kills.  There have been reports of hospitalizations after wet cupping, so it should be completely avoided.  Wet cupping results in scarification of the skin or may use suction followed by use of a scalpel to make small cuts in the skin to let blood, followed by a second suction cupping treatment.  This is thought to eliminate scar tissue.  Because cupping was described as having been used by Mohammed, many Muslim countries still use cupping and wet cupping (fire cupping) with its bloodletting is used in China frequently..  The American Cancer Society and most guidelines for use of alternative therapies have concluded cupping has no health benefits at all.   

Alpha levels of evidence- No recommendation for or against due to widely varying outcomes (J Altern Complement Med. 2017 Nov 29);  for low back pain, cupping in a meta-analysis demonstrated mild reduction in VAS pain scores and significant reduction in disability (J Back Musculoskelet Rehabil. 2017 Nov 6;30(6):1187-1195).  Cupping therapy only minimally improves knee arthritis (Complement Ther Clin Pract. 2017 Aug;28:152-160)  The latter two studies are Chinese studies, and therefore highly suspect.  With regard to wet cupping 9 RCTs favored wet cupping while 5 did not. ( Altern Complement Med. 2016 Oct;22(10):768-777. Epub 2016 Aug 24. Review.)  A Chinese study demonstrated wet cupping reduces pain due to Shingles (Altern Ther Health Med. 2010 Nov-Dec;16(6):48-54).  Wet cupping was not found to be recommended in a Cochrane database for acne vulgaris (Cochrane Database Syst Rev. 2015 Jan 19;1:CD009436)  A study of miniscalpel-needle use of relief of myofascial pain in a Chinese study showed improvement but because of randomization problems in the study, there was concern over the outcomes  PLoS One. 2015 Feb 24;10(2):e0117146. doi: 10.1371  Other studies: 

  • J Back Musculoskelet Rehabil. 2017 Nov 6;30(6):1187-1195 A meta-analysis of randomized trials demonstrated significant effectiveness for the treatment of low back pain

  • J Pain. 2009 Jun;10(6):601-8. Cupping of the trapezius for carpal tunnel syndrome led to significant reduction in pain (RCT)

  • A systematic review of studies in 2011 (Evid Based Complement Alternat Med. 2011;2011:467014) it was found there were two randomized controlled trials showing some benefit in pain treatment and one that found no benefit. Overall, the quality of the available studies being conducted by those using cupping are so poor that no conclusions may be drawn about efficacy. 

Injuries from cupping, while rare, may be serious.

  • Interv Neuroradiol. 2016 Dec;22(6):728-731 Cupping was associated with a vertebral artery rupture and large hematoma on the back of the neck

  • Wounds. 2014 Jul;26(7):214-20.  Burn injuries from cupping in China are not uncommon, more often seen with wet vs. dry cupping

  • J Dtsch Dermatol Ges. 2015 Apr;13(4):337-8  Cupping may cause permanent dermal scarring

  • J Cutan Med Surg. 2015 May-Jun;19(3):320-2  Cupping may induce psoriasis in areas under the cups

  • J Burn Care Res. 2011 Mar-Apr;32(2):e31  Burn injuries due to cupping

  • J Altern Complement Med. 2009 Nov;15(11):1243-5.  Cupping may create severe blistering as well as bruising

Dance/Movement therapy (DMT)- represents the fusion of movement in the form of dance to combat fatigue, balance issues, and chronic pain.  Although considered experimental by insurance companies.  The journal Arts in Psychotherapy (Vol 41(1), pp 46-64) published a meta-analysis of studies on DMT in 2014 and found moderate effects for quality of life and clinical outcomes (depression, anxiety) and small effects for improvement of well-being, mood, affect and body image.  There was no specific analysis for pain reduction but frequently improvement in depression and anxiety leads to reduction in pain.   Painbytes recommendation: one thumb up.  Some research indirectly involving pain

 

Digital myography-  

 

Ear Candling – is also called “auricular candling”, coning or “thermo-auricular therapy”, and refers to procedures that place a cone shaped device in the ear canal extracting earwax and other impurities with the aid of a burning wick or smoke.  It is used to improve general health and well-being, to purify the blood, and cure cancer.  Medical research has shown it is both dangerous and ineffective, and fails to remove either earwax or toxins, and has no effect on cancer.   The potential for burns to the face or of hot wax dripping into the ear poses real safety concerns.   Painbytes assessment: two thumbs down.  This is a potentially dangerous procedure, does nothing useful, and should be avoided.

Ear Seeds- these are small seeds of a plant such as the vaccaria plant (small black seeds) that serve the place of pellets in providing autoauricular therapy.  The seeds are attached to the ear with adhesive tape and then stimulated once an hour with the fingertips to support the production of a healing of one of many maladies thought by those believing in auricular therapy .  There is virtually no significant scientific research to support the use of ear seeds. 

Eclectic medicine- This is mentioned only for historical purposes as this was a medical system in the US existing from 1820-1939 when the last eclectic medical school closed.  Eclectic medicine had its roots in early American herbal medicine and was an extension of Thomsonian medicine and Native American medicine.  At the time of its initiation in the 1820s, standard medical practices at the time extensively used cathartic purges using calomel and other mercury based remedies as well as extensive bloodletting- practices common in Europe.  Eclectic medicine was a reaction to those practices that they considered barbaric and also Eclectic medicine was an attempt to restrict Thomsonian medical innovations (herbal medicine) to medical professionals.  Eclectic medicine had numerous medical schools with one of the earliest being the Reformed Medical College of New York in 1837.  In 1833, the Eclectic Medical Institute in Worthington, Ohio graduated its first class in 1833, then the school moved to Cincinnati in 1842. Training in these institutions were in physiology and conventional medicine along with herbal and botanical medicine. By the 1850s, the influence of the dozen medical schools of eclectic medicine was becoming widespread and standard medical doctors began using herbal salves of Eclectic medicine.  Eclectic medicine was in competition with other forms of medicine that were on equal footing in the 1800s and early 1900s including homeopathy (there were many homeopathic hospitals at one time), native American medicine, chiropractic, osteopathy, and standard medicine.

Egoscue method- Is a physical therapy postural correction designed to “Stop Chronic Pain”.    This system is taught through “Egoscue University” that offers proprietary method courses that are online in several different levels.  Generally 6 months is required for the level of certification required to open a clinic.  It does not seem according to the website that any prerequistes are required.  The patients are taught “E-cises” that are designed for postural correction that is stated on the egoscue website to reduce pain.  Egoscue’s method is based on many older methods including chiropractic, osteopathic, feldenkrais, rolfing, yoga, etc and is in no means revolutionary, but is an excellent synthesis of other ideas.   Peter Egoscue appears to believe his method can cure pain but there is little evidence in the literature for this.  Painbytes assessment:  movement and posture methods are generally favorable for pain therefore even in the absence of specific proof for this, a mildly positive recommendation is given to the Egoscue method.

 

Electrodermal stress analysis- Also known as electrodynamic screening (EDS), electrodermal testing (EDT), bioelectric functions diagnosis (BFD), bioresonance therapy (BRT), bio-energy regulatory technique (BER), biocybernectic medicine (BM), computerized electrodermal screening (CEDS), computerized electrodermal stress analysis (CEDSA), limbic stress analysis (LSA), meridian energy analysis (MEA), point testing, etc.  It is a simple galvanometer measuring electrical conductance of the skin with the operator applying a probe over acupuncture points on the other hand.  Readings higher than 50 indicate inflammation and lower readings mean organ stagnation and degeneration.  The operator can control the readings by varying the amount of pressure, the angle of the probe, or the amount of moisture on the skin.  The operator asks the patient a series of questions that have yes or no answers.  The patient’s subconscious is touted to know the intention of the machine or operator, and the operator must be a believer due to the “quantum link” between the operator and patient’s mind will interfere with the patient’s response.  The hands have points for diagnostics including the adrenal, circulation, jaw, hypothalamus, ileocecal valve, heart, allergies, protein metabolism, fiber, uric acid, carbs, etc.   The science behind this technology is very unproven and is simply speculative and there is no underlying scientific basis to suggest there is anything to this technology.  It appears to be more of a belief system rather than any meaningful medical diagnostic technique.  Painbytes rates this two thumbs down.

 

Electrodiagnosis according to Voll (EAV)- see above entry

Electrohomeopathy- also called Mattei cancer cure, is a 19th century invention of Count Cesare Mattei (1809-1896)  based on homeopathy developed by Hahnemann in the 18th century with the addition of the concept of "bio-energy content extracted from plants".  To contrast,  homeopathy uses extracts of plants, animals, and minerals.  It was popular in the late 19th century.  Mattei believed there was "electricity" in botanical extracts and made bold, unsupported claims for the efficacy of his treatments including treatment of cancer.  Mattei believed different biological extracts contained red, yellow, blue, green, and white electricity.  There were three journals of electrohomeopathy at the beginning of the 20th century but interest in this system has waned. According to electrohomeopathy, all diseases were due to changes of the blood or lymphatic system, and therefore remedies were broadly divided into two categories to be used in response to either blood or lymphatic disease.  Electrohomeopaths believe diseased organisms are far more sensitive than healthy organisms and changing the condition of the bodily fluids will work on the cause of the disease.  Mattei would select the plant extract that was extremely diluted, that contained the kind of "vegetable electricity" needed to cure.  Now electrohomeopathy is practiced predominately in Pakistan and India, but some immigrants bring it with them to the US. Interestingly, the electrohomeopaths believe a complex mixture is needed to cure disease contrasted to Hahnemann (the originator of homeopathy) who believed only one agent should be employed.   LEVEL OF EVIDENCE: There are no scientific articles in the National Library of Medicine regarding electrohomeopathy therefore its use is purely speculative, based on hope rather than on any proof of safety or efficacy.

Electromagnetic therapy- the application of low gauss electromagnets have been used by alternative medicine practitioners for over a hundred years for a variety of purposes, including cell growth promotion, pain reduction, improved blood circulation, bone repair, increased wound healing, sedative effects, enhanced sleep, and arthritic relief.  Most of the claims have been disproven, however there is low level alpha evidence in 2 out of three trials for venous leg ulcers healed faster with EMT. (Cochrane Database Syst Rev 2015 Jul 2(7):CD002933)   There is alpha evidence of reduction of pain by 1.5 points on the VAS scale but no significant improvement in function for those receiving electromagnetic therapy for arthritis (Cochrane Database Syst Rev 2013 Dec 14(12): CD003523)  There is marginal beta evidence in a small trial using EMT for treatment of healing of pressure ulcers (Cochrane Database Syst Rev 2015 Sep 3(9):CD002930)  There is beta evidence pulsed electromagnetic field therapy may be useful to treat adhesive capsulitis of the shoulder with 30% pain relief vs 0% for placebo (Cochrane Databse Syst Rev 2014 Oct 1;(10):CD011324).

Emotional Freedom Technique (EFT)- This is a therapy developed by Gary Craig largely based on Thought Field Therapy (TFT) developed by Roger Callahan for the treatment of anxiety disorders and emotional distress.  EFT incorporates a combination of neuro-linguistic programming, energy medicine, and acupressure into a hodgepodge of concepts.  Alpha level evidence from 2009 showed flaws in the studies but that there were reported “small successes” for EFT.  A 2016 systematic review found “EFT was effective in reducing anxiety compared to controls” (The Journal of Nervous and Mental Disease. 204 (5): 388–395. )  Similar to the recommendation for TFT, there is a limited positive support for this therapy that had previously been dismissed as quack therapy by the medical and scientific community.

 

Essential Metabolics Analysis (EMA) or Essential Metabolic and Fatty Acid Analysis (EMFA)- is a laboratory analysis of the blood for fatty acid ratios (omega 6/omega 3 ratio) that is purported without significant scientific backing, to be indicative of the general state of inflammation of the body.   The inflammatory state of the body is thought by physicians that buy into this to be a purveyor of disease.  There are some doctors that take the animal research or molecular research and apply it directly to human disease, effectively believing they can cure or curtail the ravages of many disease with dietary changes and supplements.   While there is little evidence this works, it does provide some doctors with a very healthy supplement business.   Labs are profiting greatly from these analysis with some analyzing up to 24 fatty acids in the blood and calculating a host of ratios, the significance of most are speculative.  Insurers such as Aetna consider this to be experimental and will not pay, therefore the cost of such analysis comes out of the patient’s pocket.  Especially homeopathic doctors and naturopathic doctors strongly subscribe to these notions of fatty acid significance and attempt to sell the patient even more uncovered treatments, the supplements.    That being said, there is evidence that treatment with omega 3 fatty acids improves chronic headaches (Pain. 2013 Nov;154(11):2441-51), alpha linoleic acid plus superoxide dismutase improves low back pain (Eur J Phys Rehabil Med. 2013 Oct;49(5):659-64), N-palmitoylethanolamine plus transpolydatin improved endometriosis pain (Eur J Obstet Gynecol Reprod Biol. 2013 Jun;168(2):209-13), and Palmitoylethanolamide 600mg twice a day reduced multiple source chronic pain (Pain Med. 2012 Sep;13(9):1121-30).  However, the use of these substances as a treatment does not require measurement of these substances in the blood.

 

Essential Oils- see aromatherapy

Essiac tea- touted as an anticancer tea, an anti-inflammatory drug, and immune boosting drug, this tea is a mixture of four different herbal medicines: burdock root, sheep sorrel herb, slippery elm bark, and Turkey or Indian rhubarb root.  The name Essiac is the name of the nurse spelled backwards (Caisse) who was given the formula in the 1920s by a patient and claimed it was an ancient Indian (American) tea.  She used it to treat cancer in Canada, then the drug was submitted to the FDA in the US for approval and was rejected.  Canada rejected the drug, and the nurse continued to make the tea anyway and give it away.  There are almost no scientific studies proving efficacy of the tea.

 

Faith healing- Randomized trials have shown faith healing has no effect on health outcome.  Intercessory prayer did show a very small improvement in pain.  The primary finding was that unless the person believed in prayer initially, there was no detectable insurance (2004 Jun;10(3):438-48 Journal Altern Complement Med) was there any improvement.  There are no published randomized or series trials on faith healers effect on pain or any malady.  That being said, prayer is frequently used in chronic disease in the US and around the world, and certain ethnicities employ prayer more than others (Pain Manag. 2014 Nov;4(6):389-406).  On the contrary, high degrees of religiousness are directly related to the presence of headaches. (Cephalalgia 2015 Mar;35(3):240-7).  Faith healing is distinct and separate to spiritualism or religious beliefs of the patient since in the latter two issues, these are integrated into several healing systems including yoga, etc.

 

Fangotherapy- Fangotherapy is the name of a spa body treatment in which mineral-rich thermal mud, clay or peat is spread over the body for the purpose of purification, revitalization, deep cleansing and to help reduce bodily toxins.   It is similar to balneotherapy and dissimilar to hydrotherapy.

Some fangotherapy sessions include bathing in the mud (mud baths), others include mud massages, while others involve the simple application of the mud to the skin.  

Analgesic and detoxifying mud baths have been used since ancient times to minimize muscle aches and pains, is will purportedly “draw out toxins” from the skin and body and help ease conditions such as osteoarthritis, rheumatoid arthritis, immune disorders, cardiac disorders, fibromyalgia, tuberculosis, acne, psoriasis gout and chronic dry skin. Fangotherapy techniques also increase blood circulation, which opens follicles, aids in nutrient/waste exchange and increases skin elasticity. 

 

Fangotherapy gets its name from the Italian word “fango,” which means mud. The most popular place to receive therapeutic fangotherapy is at one of the many spas located in either Abano or Montegrotto Terme, two towns located in the volcanic Euganean Hills of Italy.   The results are the same scientifically as balneotherapy

Feldenkrais method of exercise therapy (also known as awareness through movement).  It was developed by Moshe Feldendrais, born in the Russian Empire in 1904 and died in Israel 1984.  He was educated at the Sorbonne in Paris.  He developed the technique after suffering a soccer injury.   This is considered experimental by Aetna and some other insurances.  This is a movement therapy designed to reduce pain or limitations in movement.  It is designed to improve physical function and to promote generalized wellbeing by increasing student’s awareness of themselves.  The technique was partially based on the Alexander technique developed half a century earlier.  Feldenkrais taught increasing a person’s movement and proprioceptive (position sense) self awareness could reduce pain and bring greater ease and pleasure of movement.  It involves training and certification of practitioners, many of which are physical therapists and others involvement in movement therapies.  This has been shown to be an effective therapy for chronic neck pain on several outcome measures in a randomized trial (Arch Phys Med Rehabil 2014 Sep;95(9):1656-61).  However another randomized trial did not report any improvement in osteoarthritis pain or quality of life after a 30 week session of Feldenkrais. (Evid Based Complement Alternat Med 2013;2013:479142).   Painbytes assessment is neutral given the varied results.

 

Flower essence- involves the use of extracts of flowers as a type of treatment for a number of conditions.  The Flower Essence Society is the main purveyor of this alternative medical system.  They have many publications for sale on their website and make many claims.  Their “proof” largely consists of case studies without any controls.  They claim extracts or “essences” are treatments for insomnia, depression, and a variety of other maladies.  There is virtually no scientific proof these treatments are effective.  However they are probably not harmful.  Painbytes assessment is one thumb down due to the lack of science.   www.flowersociety.org

 

Fresh cell therapy – is an alternative medical therapy purported to reverse the aging process and to heal chronic diseases, “to improve vitality, stabilize mental power, strengthen the immune system”.   This therapy is touted to heal a variety of issues including liver disease, sexual dysfunction, diabetes, cerebral palsy, multiple sclerosis, heart problems, etc.   The process involves injecting cells or cell components of animals into humans, particularly from the sheep.  Some practitioners use freeze dried cells or tissues for injection.  There is no scientific proof this therapy works and may lead to life threatening reactions.  Many countries ban this type of therapy.   Painbytes assessment is two thumbs down since it may cause serious side effects and is being used with virtually no scientific proof of effectiveness.

 

Functional intracellular analysis
- is also called micronutrient testing.  This test is an intracellular (as opposed to the usually performed serum) analysis of vitamin and mineral levels.  Advocates claim that intracellular nutrient status is superior to serum testing, however there is little proof of this.  The relationship between serum and intracellular levels of micronutrients is complex.  The balance depends upon a number of factors including the physiology of cellular transport mechanisms and the individual cell type.  Aetna, some Blue Cross insurers, and others consider the testing investigational, ie. without scientific proof of effectiveness.  Functional intracellular analysis is frequently used by chiropractors who lack the ability to prescribe medications, and instead rely on nutrients as an ineffective way to treat many diseases.  Joint pain is produced by hypothyroidism and chiropractors address joint pain in some cases with nutrients.  Painbytes assessment: two thumbs down.  This type of analysis is indeed an alternative medical system with little science behind it and can cause serious injury to patients needing traditional medical care.

Functional medicine- This is an alternative medical system invented out of thin air by a nutritionist (not a physician) Jeffrey Bland, who was cited by the Federal Trade Commission in 1991 for false claims his company's products altered metabolism and induce weight gain. Four years later the FTC found Bland violated that consent order by making more exaggerated claims that his diet provided relief from GI problems, inflammatory and immunologic problems, fatigue, food allergies, mercury exposure, kidney disorders, and rheumatoid arthritis.  He was forced to pay civil penalties to settle such false claims.  Functional medicine focuses on "interactions between the environment and the gastrointestinal, endocrine and immune systems".  Practitioners develop individual treatment plans for people they treat.  Functional medicine is vaguely defined, centering on expensive blood tests and urine testing as part of "holistic" healthcare.  Proponents eschew established medical knowledge, instead adopting a model of disease based on the notion of "antecedents", "trigger", and "mediators" that are meant to correspond to the underlying cause, the immediate cause, and the particular characteristics of a persons illness. A functional medicine practitioner develops a "matrix" from these things which acts as a basis for treatment.  Functional medicine embraces orthomolecular medicine (megavitamin therapy), detoxification of unspecified and unidentifiable toxins, biochemical individuality, diagnosis of chronic occult infections that modern medicine frequently dismisses based on the lack of evidence such as chronic Lyme disease, homeopathy, biopuncture- the injection of homeopathic remedies, scientifically unproven nutritional interventions especially the avoidance of gluten for everyone regardless of whether they have any demonstrable gluten intolerance, leaky gut syndrome treatments, and is an anti-vaccine extremist.  There is no more scientific evidence of functional medicine than any of the parts of functional medicine, which is virtually none.

Gua sha- a traditional Chinese medical practice using a stone, sharpened porcelain spoon, steel edge, or jade stone to create dermabrasion lines from the spine outwards, causing extreme redness to the skin in areas of gua sha application.  It is used frequently by the Chinese after an oil massage to begin with. The term "sha" refers to the petechia or extravasation of blood along the lines of applying these instruments that literally scrape the skin.  The Chinese use these techniques for the treatment of many maladies including active hepatitis B, migraines, shoulder pain, back and knee pain, fever, flu, earaches, asthma and bronchitis.  It may attract the attention of American physicians who generally oppose the technique, and it may be confused with child abuse in young adults and children.  Because it is so common among those from China and Southeast Asia, many patients avoid modern physicians due to their vocal opposition to patients using the technique.  Gua sha is very similar to coining.   There is very little medical evidence of effectiveness (Chin Med. 2010 Jan 29;5:5. doi: 10.1), but there are many poorly constructed low level studies in the Chinese and Western literature.  There are some basic science experiments showing an anti-inflammatory effect but practitioners using these are engaging in a leap of faith to translate these into human results, and at best are engaging in defrauding of patients claiming there is science to support Gua sha as of 2018.  As usual, the Chinese medical literature does not translate to reproducible results in Western medicine since 1. the Chinese do not use standards for constructing randomized controlled trials,  2. have a high bias rate compared to Western studies, and 3. rarely use a specific technique alone- the Chinese throw many techniques and treatments at a disease or condition at the same time, hoping something in the combination actually works.  Therefore Western medicine is prudently skeptical about any results from China or Chinese practitioners until they can meet the more rigid standards of conducting scientific experiments. 

Gemstone therapy-  See crystal therapy

 

Gerson therapy- is a dietary system for curing diseases that are theorized to be caused by toxicity and nutritional deficiency.  The system uses “coffee enemas” to “eliminate toxins from the liver” and consuming up to 20 lbs of organically grown fruits and vegetables every day in the form primarily of raw juice extracts.   The diseases  purportedly cured by this system include tuberculosis, cancer, and migraine headaches in addition to a laundry list of other diseases.   There is very little evidence such a system cures anything, the coffee ground enemas have been shown to do virtually nothing, however the beneficial effects of the nutrients may have a modest positive effect on overall health.   Painbytes assessment is one thumb down due to claims of disease cures without any proof or evidence.

 

Gestalt therapy: This psychotherapy aims to help the client achieve wholeness (gestalt is the German word for whole) by becoming fully aware of his or her feelings, perceptions, and behavior. The emphasis is on immediate experience rather than on the past. Gestalt therapy often is conducted in group settings such as weekend workshops.

 

Glyconutrients- a controversial treatment to improve memory and increase anti-oxidant levels.  Glyconutrients are effectively one of the 8 essential sugars used by the cells in the human body.  Unsubstantiated claims by Mannatech, one of the largest manufacturers of glyconutrients caused several lawsuits by both the state and federal authorities resulting in settlements by the company and huge losses year by year.  The multilevel marketing of the company and false claims of medical treatment claims by their sales staff has severely crippled the company in addition to many expert scientists that believe the only effect of glyconutrients is the development of flatulence.  Painbytes assessment:  2 thumbs down.  Shady marketing practice with very little scientific support.

 

Graston technique- see massage

 

Guided imagery- is effectively using the imagination to image a desired future or cellular level processes in addition to others.  Guided imagery uses primarily the visual, but also subconscious imagery.  The proponents claim it has the capacity to deliver layers of complex, encoded messages by way of simple symbols and metaphors.   It is claimed it can heal many diseases, lower cholesterol, heighten the immune system, reduce blood loss during surgery, and lessen pain and headaches.  It can purportedly increase skill at skiing, skating, tennis, writing, acting, and singing, and can induce weight loss and reduce anxiety.   While most of the claims are non-sense, it cannot be argued that there is some evidence of marginal effectiveness in improving depression in fibromyalgia patients and a slight and barely statistically significant improvement in pain. (Holist Nurs Pract 2015 Jan-Feb: 29(1):13-21)  however another randomized control trial found no effect of guided imagery on fibromyalgia (J. Health Psychol 2014 May; 19(5):678-88).   A slight effect of graded motor imagery was found in a systematic review of all randomized controlled trials for chronic pain. (J. Pain 2013 Jan; 14(1):3-13).  A review of the clinical trials of guided imagery for non-musculoskeletal pain demonstrated a significant reduction of pain in 11 out of 15 trials but the quality of the trials was generally poor.  (J. Pain Symptom Manage. 2012 Jul:44(1):95-104)   A review of the clinical trials of guided imagery for musculoskeletal pain showed significant reduction of pain in 8 out of 9 trials but the quality of the trials was generally very low.  A clinical trial showed decrease pain, anxiety and improved mood and quality of life in patients with inflammatory bowel disease (Psychol Health 2012:27(12):1463-79).   Although guided imagery is considered “investigational” by some insurers, it is clear there are some positive benefits, the therapy can be self directed and is therefore inexpensive, has no significant negative impacts, does not require proprietary equipment or training.  Painbytes assessment is one thumb up.

 

Hair analysis- has many meanings including the alternative medicine analysis of hair for “toxins” and proteins, the use of hair analysis to determine food allergies, the forensic analysis of hair for arsenic or matching other hair or for DNA, the analysis of hair for illicit substances, and microscopic evaluation of hair structure to determine the causes of hair loss.   Most insurers consider most of these to be experimental and do not cover them.  Guidelines from the National Institute for Health and Clinical Excellence (NIAID) and the American Academy of Asthma, Allergy, and Immunology both recommend against the use of hair analysis in food allergy and diagnosis or rhinitis respectively.   The AMA has warned against the use of hair analysis to determine whether supplement levels are adequate as this remains completely speculative.  Since hair will contain different levels of minerals and trace elements varying with blood levels as hair grows, it is impossible to accurately determine the levels of minerals in the body because every millimeter of hair would have to be analyzed separately.    Falsely elevated cortisol level in the hair analysis when a person sweats that leads to elevations in cortisol levels that cannot be washed out. In 1985, 13 commercial labs independently tested the same hair sent to them and had wildly differing results.  The labs all had significantly differing "normal" values, and the mineral levels obtained were entirely inconsistent from one lab to the next. Six of the labs recommended food supplements but the types varied widely from one lab to the next. Many of the labs suggested "abnormal conditions" were present in the normal patients.

Painbytes analysis:  two thumbs down.  The results are speculative and may lead to harm if therapies are introduced using this data.

 

Hako-Med machine (electromedical horizontal therapy)- is specifically considered experimental and investigational by Aetna, some Blue Cross insurers, and several other insurers.  Apparently it is a high frequency electrical stimulation

System that is advertised by the manufacturer for treatment of post-traumatic pain syndromes, management and relief of chronic pain and post surgical pain, relaxation of muscle spasms, prevention or retardation of disuse atrophy, increasing local blood circulation.  Some of their products appear to have pneumatic compression devices.

Hako-med is a device that has been named in fraud litigation against physicians that miscode the therapy to defraud insurers ostensibly due to lack of insurance coverage (http://www.justice.gov/usao/gan/press/2007/02-20-07.pdf).  Hako-med also advertised on their website that most insurers cover the device but in my research, some of the largest insurers do not.  There is some clinical evidence of effectiveness in spinal fractures  (http://www.hakomed.net/files/07_low_back.pdf) and for some arthritis treatments.  This appears to be used as a significant revenue generator for physician offices with one physician, Dr. Nevada Lee, MD on the manufacturers website claiming the hakomed “helped us survive the first two years of my practice”.

Hakomed also lost patent infringement lawsuits and appeals by a competitor in 2010 and 2011.   A chilling tale of how Hako-med treated a distributor who found he could not sell the devices due to physician’s concern over lack of reimbursement and with an independent assessment of appropriate billing codes resulted in much lower values for reimbursement if coded properly.  Hakomed effectively determined that the distributor could not lease the units out, demanded “recertification” fees in the amount of $10,000, and threatened physicians doing business with the distributor may be found at http://www.gas.uscourts.gov/usbc/publishedopinions/lwd/09-04002-LWD-95.pdf  

Painbytes assessment of Hakomed:  Two thumbs down based on their business dealings and lack of insurer coverage.  The machines were sold to distributors for $22,000 each to be sold at higher values to physicians.  With reimbursement from insurers lacking due to exclusion by insurers as “investigational”, physicians will likely pass on relatively high treatment costs to patients.  There are few clinical trials supporting this therapy.

 

Hellerwork- was a modification of Rolfing, since Joseph Heller trained for 6 years with Ida Rolf.  In addition to the connective tissue manipulation and massage, Heller added movement education and verbal dialogue.   The movement education is focused on educating about sitting, standing, and walking.  The verbal dialogue is designed to teach awareness of interrelationships of the body, emotions, and attitudes.  Hellerwork consists of eleven $100 sessions .  Aetna insurance considers this to be experimental and is not a covered benefit.  Painbytes is neutral on recommendations with the movement therapies showing modest benefit, massage showing modest benefit, countered by the high out of pocket cost of this therapy.

Hijama- see cupping

 

Homeopathy: This is an alternative medical system that subscribes to several unvalidated and unscientific concepts as the basis of its foundation.  Samuel Hahnemann, a poorly trained German physician wandering vagabond that had given up medicine and had taken up translating medical books, in 1796 noted that the drugs of the day (we would call them supplements today) were toxic and frequently led to increased sickness and that bloodletting did more harm than good.   He developed the doctrine of “like cures”,  “that which can produce a set of symptoms in a healthy individual, can treat a sick individual who is manifesting a similar set of symptoms”.  This bizarre concept came out of his notation that cinchona bark (used to treat malaria) induced malaria like symptoms when he took the bark, therefore the bark could be used in the sick to treat the sick.  He then did a series of experiments on different medicines, cataloging the side effect profiles of the different drugs, then finding disease that had similar symptoms, drawing the incorrect conclusion that these drugs could be used to treat the sick since their side effects were the same as the symptoms produced by the disease.  In 1800 he began diluting the medicines to the extreme, a process he called incorrectly “potentization”.  He developed the notion that even though the dilution was so extreme that there were statistically no molecules of the original drug left in the final solution, that the water had “memory” of the healing power of the diluted drug.  The process of dilution was denoted by the term “C” to denote the number of dilutions 1:100 of the original substance (Hahnemann developed this scale he called the centesimal scale).  Therefore a 30C on a bottle means he has diluted the original 1 part to 100 parts distilled water, then repeat this process 29 more times.  This is equivalent to 10-60 concentration or no molecules at all of the original substance.  Anything with higher dilution factor than 12C has no molecules of the original substance remaining.  After each dilution and mixing, the container is struck against an elastic piece, somehow locking in the memory of the original molecule. Hahnemann believed without any scientific or mathematical justification, that with each dilution the solution becomes more potent.  Scientifically this process results in the existence of sterile water alone in the final dilution and homeopathic stores charge significant money for this sterile water.  Hahnemann also believed that the “dynamization or shaking of the solution” produced a “spirit-like” healing force to be released from within the substance.  In 1828 Hahnemann fixed 30C as the standard potency for all homeopaths.

 

In addition to the other bizarre concepts embraced by Hahnemann, he developed his theory of diseases that are caused by “miasms”.  A miasm is a word meaning a cloud or fog in the being.  Homeopathy teaches (via Hahnemann) that all diseases are caused by one of three miasms and that 85% are caused by the Psora miasm.  All non venereal chronic diseases are Psoric including most diseases of a chronic nature, all skin diseases, most mental illness other than syphilitic ones, allergies, varicose veins, hemorrhoids, and organ dysfunctions.  Hahnemann claimed that Psora is the most ancient and insidious miasm, derived from skin eruptions of various types in the past such as scabies, leprosy, and psoriasis that were contracted by ancestors.  Remedies include sulphur, graphite, phosphorus, mezereum, causticum, hepar sulph, petroleum, silica, zinc, psorinum, arsen alb, lycopodium, calc carb, natrum mur, etc.

It appears in many of the writings of homeopaths, it is believed Psora is a state of susceptibility to disease from willing evils, and that effectively most disease exists because of the sins of mankind.

Sycosis is a miasm responsible for many sexual and urinary disorders, arthritis, and mucous membrane diseases, including asthma, bronchitis, and warts.  This miasm was thought to derive from gonorrhea. Remedies are Thuja, Lycopodium, Natrum sulph, Causticum, Kali sulph, Staphysagria, Calc and Sepia amongst others.

Syphilis is the third miasm and is responsible for diseases of the nervous system, blood, skeleton, and psychological disorders, deafness, blindness, and ulcerations and nocturnal skin eruptions.  Remedies are Arsenicum, Aurum, Mercury, Phosphorus and Lycopodium, nitric acid

 

He also developed a theory in 1803 that many diseases were caused by coffee.  This medical system uses minute doses of natural substances- called remedies-to stimulate a person's immune and defense system. A remedy is chosen individually for a sick person based on its capacity to cause, if given in overdose, physical and psychological symptoms similar to those a patient is experiencing.

 

Homeopathy remedies are readily available over the counter now and all drug stores and many grocery stores.  Some have been adulterated by using high concentrations of standard medical drugs such as corticosteroids and theophylline since the homeopathic remedies doe not work according to most scientific studies.  The FDA does not regulate homeopathic remedies, does not require safety or efficacy studies, and does not require analysis of the products being sold to the public for toxins or adulterants.  Homeopathy fits the definition of quackery established by the US House of Representatives. 

 

Homeopathy and Pain:  Homeopathy not significantly different than placebo studies: Double blind randomized placebo controlled trial for knee osteoarthritis J Evid Based Complementary Altern Med 2015 Jan 30.   Homeopathy remedies doe not help with rheumatoid arthritis (Rheumatology (Oxford) 2011 Jun: 50(6);1070-82)   Topical arnica was found to make muscle pain worse rather than better (Ann Pharmacother 2010 Oct;44(10):1579-84)   Traumeel S is no better than placebo for post operative pain (BMC Clinic Pharmacol 2010 Apr 12;10:9).  Homeopathy does not reduce morphine consumption after knee ligament surgery (Br J Clin Pharmacol 2008 Feb;65(2):180-7)

 

Painbytes assessment:  Two thumbs down.  This bizarre antiquated system lacks any support in science and adopts ideas and treatments that have been disproven.  Disease is considered due to the sins of mankind.  The National Council Against Health Fraud recommends consumers not to buy homeopathic products or to patronize homeopathic practitioners.

 

Human placental tissue- is an excellent source of immature stem cells capable of transformation into almost any tissue in the human body.  The FDA in 2014 approved the placental cells for injection.  There are very few specific studies of this tissue but there have been publications in 2012 showing the cells can differentiate into any organ- that is, they are called pluripotent.  Either fresh or frozen stem cells can be used.  Although the potential is for use is extraordinary, given the unknown risks and nascent state of the science, it would be better to wait a bit before engaging in this therapy.  Painbytes assessment: one thumb down as of 2/15.

 

 

Humor therapy- aka therapeutic humor and sanctioned by the Association for Applied and Therapeutic Humor (yes, this is real), is using the power of smiles and laughter therapy to reduce the impact of disease.   Therapies employed include humorous videos, stories, laughter clowns, raucous simulated laughter, and Laughter Yoga.   In studies, laughter does appear to change the brain chemistry and boost the immune system, in addition to reduction of the impact of depression and anxiety.   There are studies demonstrating laughter therapy reduces pain in radiation dermatitis patients, especially the more severe dermatitis (Onco Targets Ther 2014 Nov 4:7:2053-9).  Benefits of laughter include reduced anger, anxiety, depression, and stress; reduced tension (psychological and cardiovascular); increased pain threshold; reduced risk of myocardial infarction (presumably requiring hearty laughter); improved lung function; increased energy expenditure; and reduced blood glucose concentration. However, laughter is no joke-dangers include syncope, cardiac and oesophageal rupture, and protrusion of abdominal hernias (from side splitting laughter or laughing fit to burst), asthma attacks, interlobular emphysema, cataplexy, headaches, jaw dislocation, and stress incontinence (from laughing like a drain). (BMJ 2013 Dec 12;347:f7274). 

There are not many high level studies using humor therapy and insurances may balk at payment, but in general given the costs being minimal and given materials that are inexpensive, Painbytes gives humor therapy one thumb up. 

 

Hydrazine sulfate- is a disproven treatment for cancer and is now mainly used in alternative medicine for the treatment of nausea and vomiting from cancer.  One of the drug’s side effects is nausea.  This is one of the therapies that showed anecdotal promise but as more and more rigorous trials were conducted it became apparent it has no effects on cancer whatsoever.  This does not stop charlatans on the internet from making such claims, and the drug (called a “supplement”) is being sold online.  The side effects include difficulty in fine muscle control, inflammation of the nerves, dizziness, and rare liver and kidney failure. 

Painbytes assessment: scam therapy.  Two thumbs down.

 

Hydrogen peroxide therapy- (drinking it or injecting it intravenously) has been touted as an effective treatment for everything from HIV to pain.  There are very few studies in humans on any of these treatments and the results and safety are speculative.  Drinking or injecting concentrated hydrogen peroxide releases significant amounts of oxygen in the blood, and the bubbles have cause brain infarction, rupture of the bowel, and cause heart failure due to bubbles blocking the output tract from the heart.  Additionally, painful gastric distension, vomiting, vomiting blood, blistering of the mouth and esophagus, laryngospasm, confusion, coma, convulsions, and death may ensue within minutes of injections. (Toxicol Rev. 2004:23(1):51-7)   Painbytes assessment:  Two thumbs down- serious safety issues and lack of evidence.

 

Hydrolysate injections- a patent was filed in 2010 for cerebroprotein hydrolosate for treating brain injuries and neurodegenerative conditions affecting the brain.  After loss of neurons from brain injury, the injection of this hydrolysate can stimulate neurotrophic activity (growth of nerves) within 24 hours of receiving the hydrolysate.   This has the potential to reverse or mitigate the damage from cerebral injury.  Currently there is not enough scientific evidence to support routine use but this medication is probably to be accepted as standard therapy eventually.  Current Painbytes recommendation: neutral.    It is considered investigational by many insurers.

Hydrotherapy- (hydropathy or water cure), uses water for pain relief with water jets, water massage, mineral baths, thalassotherapy, hut tubs, pool therapy, etc.). It is used by naturopathy, physical therapy, and other practitioners to stimulate blood circulation and treat symptoms of diseases.  Hydrotherapy can consist of water used externally to cleanse, reduce infections due to contamination, debridement, use of hot or cool water for thermal effects, or internal water therapy (Indian, Chinese or Japanese water therapy calls for ingestion of 1-1.5 liters of water on awakening in order to “cleanse the bowel”) or water exercise (aquatherapy).   Hydrotherapy may be delivered as a full body immersion tank, arm/leg/whirlpool, or hydromassage in which a person lies in a massage chamber and water in a rubber or plastic jacket massages the patient while the patient remains dry. 

An extension of hydrotherapy is Kneipp therapy, named for Sebastian Kneipp (1821-1897) who believed in a gentle water therapy to “strengthen the constitution and remove poisons and toxins from the body”, but also employed medicinal herbs, massages, balanced nutrition and “regulative therapy to seek inner balance”.  Regulative therapy include acupuncture, purgative procedures (especially the Aschner methods), autohemotherapy, fasting therapy, homeopathy, microbiological and physical therapies.

 

There is alpha level evidence aquatic exercise provides both small clinically and statistically improvement of pain, disability, and quality of life, at least in the short term, for osteoarthritis of the knee and hip (Cochrane Database Syst Rev 2016 Mar 23;3:CD005523).   There is also alpha evidence for the treatment of fibromyalgia with hydrotherapy and aquatic exercise  (Evid Based Complement Alternat Med 2015;2015:610615).  There is alpha evidence (meta-analysis) for use of aquatic exercise for the treatment of stable heart failure (Int J Cardiol 2015;186:22-8).  There is moderate effectiveness of aquatic exercise in the treatment of musculoskeletal conditions (Arch Phys Med Rehabil 2014 Sep;95(9):1776-86).  There is NOT strong evidence that hydrotherapy improves wound healing (J Am Med Dir Assoc 2015 Jun 1;16(6):448-69).  There is much less evidence passive whirlpool or jet therapy is beneficial, however there is beta level evidence that cold whirlpool is better than warm whirlpool for resolving range of motion limitations and pain in joints (J Athl Train. 1998 Jul;33(3):222-8.) and evidence whole body whirlpool are better than warmpacks/cold packs for myofascial pain (Ann Rehabil Med. 2013 Aug;37(4):534-40). 

 

Hypnosis/hypnotherapy-  is a time honored treatment that has a long history stretching back over a century in the US.  There is evidence it can be helpful in pain (Integr Cancer Ther 2015 Jan; 14(1):5-15).  Self hypnosis training results in significant reduction in chronic low back pain (Eur J Pain 2015 Feb;19(2):271-80).  Mechanisms research support the efficacy and positive side effect profile of hypnosis, and that multiple neurophysiological processes are influenced by hypnosis to interrupt pain.  There is some evidence in meta-analysis that hypnosis does help significantly with many aspects of post operative pain.   Cancer pain treatment is aided by hypnosis.  Fibromyalgia in a randomized trial does exhibit some improvement in sleep and global impression of change (Int J Clin Exp Hypn 2013;61(1):111-23).  The Cochrane analysis of hypnosis did NOT show effectiveness for smoking cessation (Cochrane Database Syst Rev. 2010 Oct 6;(10).  Hypnosis is not covered by some insurances including Aetna despite the positive evidence.  However hypnosis by a practitioner may be expensive, therefore promoting more self-hypnosis training. 

Painbytes Assessment: One thumb up.  Modest gains in certain types of pain or other measures affecting chronic and some acute pain states.

 

 

Insulin potentiation therapy – IPT is a concept promoted by a small number of physicians that claim without significant clinical evidence that intravenous insulin increases the effect of medications therefore lower doses of these medications can be used.  It originally was used in cancer treatments but has been used in the treatment of pain also.  The name was coined by Stephen Ayre MD of Illinois in 1986.  The theory is that the cell pores “open up” and are more receptive to other medications.  It is a technique developed in Mexico City in the 1930s.  The clinical trials were forced to be halted in 2001 after the FDA was concluded it was being run improperly.  There are no other significant clinical studies supporting its use.  Safety issues involve the potential of insulin shock and underdosing a person with chemo or other drug due to an assumed enhanced effect. 

Painbytes assessment:  Two thumbs down- safety concerns and lack of evidence of efficacy. 

 

Instrument assisted cross fiber massage- See Massage Graston

 

Inversion therapy – Inversion tables are a relatively inexpensive form of home traction frequently used for the lumbar spine issues of disc herniation.   The equipment is relatively readily available from Ebay or sports store vendors.  Although there are not many studies involving pain however there is one small randomized study that did find significant clinical improvement with 77% in the inversion group and only 22% of the control group cancelling surgery.  There was also a 12 point improvement in the Oswestry Disability Index, a measure of physical function, with inversion table therapy. ( Disability and Rehabilitation 34(17):1473-80).  All other studies at the time of this writing are case series and did show a significant percentage of patients returned to work after inversion therapy  from low back pain.  The safety issues are few but real, as are the contraindications (artificial hip and knee patients should not do this therapy, those with significant ankle pain may find this therapy increases the pain.

Painbytes assessment: One thumb up.   Low level inversion study, many traction studies (non inversion), and very limited safety studies.

 

Iridology- is the diagnosis of disease by looking at the iris of the eye, and iridologists believe “nerve fibers in the iris respond to changes in body tissues by manifesting a reflex physiology that corresponds to specific tissue changes and locations”.  This concept has been disproven over and over again, yet iridology continues to exist as a belief system that by examining the iris, disease can be diagnosed.   Those practicing this art are called iridologists.  The history of iridology is somewhat bizarre and demonstrates how dangerous it is to make unrelated connections between events.  As a child in mid 1800s, Ignatz von Peczely, a Hungarian physician, noted streaks in the eye of a man with a broken leg and the eyes of an owl whose leg von Peczely had broken many years before, therefore associated streaks in the iris with broken legs, and made the assumption one could diagnose broken legs by observing the streaks in the iris. .  By 1893, Nils Liljequist from Sweden published an atlas of the iris known as “Diagnosis of the Eye”.

Evidence of effectiveness: 

A study to determine whether iridology could correctly pick patients with colorectal cancer found that iridologists correctly detected 52% of cancer patients and 53% of control patients, making iridology no different than chance in detecting cancer.  (Ophthalmologe 2008 Jun;105(6):570-4).   Another study found iridology identified the correct diagnosis of cancer (breast, overy, uterus, prostate, colorectum) in only 3 of 68 patients that had cancer, therefore iridology was of no value in diagnosis of cancer. (J Altern Complement Med 2005 Jun;11(3):515-9).  Similarly 3 iridologists in 1979 were unable to determine normal patients from those with kidney disease with one of the iridologists deciding that 88% of normal patients had kidney disease and another judged 74% of those with kidney disease as normal.  Another study on gall bladder disease showed iridology to be incapable of determining normal from abnormal gall bladders.  The uncontrolled experiments conducted by iridologists with bias built into the experiments do show positive results, but because they are uncontrolled, the responses do not rise to the level of scientific validity. 

Painbytes assessment: Two thumbs down.  This belief system is overtly dangerous to the health of individuals given the inability to accurately diagnose disease and the propensity to diagnose normal people as having disease.  Delays in treatment in those with disease and unnecessary treatments of those without make iridology no different than a scam.

 

Juvent platform for dynamic motion therapy- using a platform that looks like bathroom scales, Juvent “adjusts” and tunes itself during the first 12 seconds, then delivers oscillations between 32 and 37 Hz at a low gravitational force of 0.3g for 20 minutes while the patient stands on the platform.  The manufacturer touts this as improving bone health, reducing joint pain, increasing muscle strength, enhancing sense of balance, increasing red blood cell and stem cell production, and helps prevent osteoporosis .  The device is bought online for $3,495.  No studies are listed on the website although the site alludes to “scientifically proven”.  It is investigational in the US as approved by the FDA.   Most of the studies show no effect whatsoever in running economy and vertical stiffness (J Strength Cond Res 2015 Jan 25), any increase in bone density Z-scores {J Rehabil Med 2015 Feb23;47(3):223-8,  J Bone Miner Res 2015 Jan 8,   },  gait function (J Neurol Sci 2014 Dec 15:347(1-2):119-23), performance recovery (Int J Sports Physiol Perform 2014 Sept 17),  improvement in knee pain from osteoarthritis (Clin Rehabil 2014, Dec 18).  The treatment does result in small improvements in back pain (24%) and even smaller improvements in function (9% Roland Morris) in non specific back pain treatment (J Rehab Med 2011 Jul;43(8):689-94) The website is www.juvent.com

Painbytes assessment: one thumb down.  There are not enough positive studies or studies with clinically meaningful improvement to recommend this therapy.  There are very few safety issues with the therapy.

Kampo- A slowly evolving Japanese version of Traditional Chinese Medicine (TCM) that was first brought to Japan in 608 AD.  Kampo medicine has changed in meaning from an all inclusive style of medicine using many modalities such as TCM does to herbology and herbal therapy in Japan.  Kampo medicine is now integrated into mainstream medicine in Japan with 72% of medical doctors there prescribing Kampo herbs. Unlike TCM that modifies herbal combinations depending on the patient and disease, Kampo medicine uses fixed combinations of herbs that are regulated like medicines in Japan. The Japanese pharmacopoeia lists 165 herbs that are used in Kamp medicine including Shitake and Reishi mushrooms.  In the US, Kampo is practiced by acupuncturists, naturopaths, and alternative medicine physicians and practitioners. . 

 

Laughter therapy- see humor therapy

Live blood cell analysis 

 

Low level laser therapy (LLLT)- is also known as photobiomodulation (PBM), low-power laser therapy (LPLT), soft laser therapy, low-intensity laser therapy, low energy laser therapy, cold laser therapy, bio-stimulation laser therapy, photo-biotherapy, therapeutic laser, and monochromatic infrared light energy (MIRE) therapy.  When applied to acupuncture points, the therapy is known as laser acupuncture.  These techniques employ a low level laser of 20-250mW at various wavelengths, durations, dosages, and frequencies for a variety of maladies, including the use of low level lasers or light emitting diodes (LEDs) as a treatment for hair restoration and musculoskeletal conditions including carpal tunnel syndrome, rheumatoid arthritis, osteoarthritis, wound healing, diabetic neuropathy, smoking cessation, TMJ disorder treatment, etc.   The treatment wavelength band seems to be primarily in the infrared spectrum.  Low level laser treatment first started in 1967.   Low level laser therapy is frequently used by chiropractors and as an alternative medicine, however the results of many studies show only short term improvement if any at all. Yet, there is some evidence of effectiveness in the alpha evidence presented here.  Bone graft healing shows a positive effect at higher power and low dose or with low power and high dose (repetitive treatments) (Photomed Laser Surg. 2017 Dec;35(12):649-658).  A review of LLLT found the therapy is effective for hair regrowth in male or female pattern hair loss.  (Lasers Med Sci. 2016 Feb;31(2):363-71.)   LLLT modestly improves carpal tunnel pain for 5 weeks but diminishes rapidly after that point (Arch Phys Med Rehabil. 2017 Jun 16).  LLLT was found to improve grip strength in patients with carpal tunnel syndrome (Lasers Med Sci. 2017 Aug;32(6):1439-1448).  The most favorable outcomes were reported in the 780-860mn wavelength range with 10 J/cm2 dosage (Physiother Theory Pract. 2017 Mar;33(3):184-197).  There is evidence that LLLT treatment of pressure ulcers is effective using the 658nm wavelength but not at wavelengths above 658nm (Lasers Med Sci. 2017 May;32(4):937-944.)   Peripheral somatosensory neuropathy including diabetic neuropathy has been successfully treated with LLLT with short term results with lasers 660-860nm, power 20-250mW, and energy density 0.45-70J/cm2 (Lasers Med Sci. 2017 Apr;32(3):721-728).  LLLT is not recommended for subacromial pain syndrome (Br J Sports Med  2016 Sep;50(18):1124-34)

.  There is low level evidence that LLLT is effective for chronic low back pain (Agency for Healthcare Research and Quality (US); 2016 Feb. Report No.: 16-EHC004-EF.
AHRQ Comparative Effectiveness Reviews.)

 

Macrobiotic diet  This diet consists of whole grains, vegetables, sea vegetables, and seeds. These natural foods, cooked in accordance with macrobiotic principles de- signed to synchronize eating habits with the cycles of nature, are used to promote health and minimize disease.

 

Magnet therapy  (also known as magnetic field therapy or biomagnetic therapy) involves using magnets, magnetic devices, or magnetic fields to treat a variety of physical and emotional conditions, including circulatory problems, certain forms of arthritis, chronic pain, sleep disorders, and stress. Treatments may be applied by a practitioner or as part of a self-care program.  Static magnets whether being placed over the sites of interest and magnetic shoes and mattresses have shown no benefit whatsoever.  Electromagnet therapy with large electromagnets are effective for migraine treatment.

Painbytes assessment:  two thumbs down for static magnets, magnetic shoes, magnetic bracelets, or magnetic mattresses.  Studies have shown these to be scams.

 

Massage

A.  Manual Massage  Massage therapy is one of the mainstays of alternative medicine therapy with a longstanding history of effectiveness in pain control.  There are different types of massage: 

  • Swedish with long strokes with oil or lotion medium pressure;

  • Shiatsu with point deep pressure over acupuncture/acupressure points-usually no soreness afterwards;

  • Deep tissue massage with focus on the deepest layers of muscle tissue, tendons and fascia with often painful massage techniques that leave the person feeling very sore for days; 

  • Sports massage focusing on specific areas of injury or pain; 

  • Hot stone massage that uses heated smooth stones placed on certain points on the body, warming and loosening tight muscles; 

  • Thai massage, like shiatsu uses gentle pressure on specific points, but also compresses and stretches you into a sequence of postures thereby increasing flexibility; 

  • Reflexology is a massage of the foot by placing pressure at specific points on the foot that purportedly correspond to organ dysfunction; 

  • Myofascial release is a specific massage technique that focuses on specific areas of tightness in muscles that pull the body out of alignment.

  • Acupressure uses physical pressure applied to acupuncture points with the aim of clearing blockages in meridians.

  • Bowen technique (Neuro-structural Integration)- named for Tom Bowen who died in 1982, a non-medical trained individual selling himself fraudulently as an osteopath, that called his approach a “gift from God”, involves gentle rolling motions along the muscles, tendons, and fascia with minimalist nature of the intervention with pauses incorporated in the treatment.   

  • Craniosacral therapy is a technique developed by John Upledger, an osteopath in the 1970s, who believed by concentrating on the suture lines in the skull, he could detect rhythms of the spinal fluid and blood flow underneath these thick bones.  He believed the same about the sacroiliac joint.  It is a relaxing therapy that has apparently no legitimate use other than relaxation as the touted diagnostics by the technique are practically voodoo. (See description elsewhere in this paper)   

  • Lomilomi is a technique of Hawaiian massage using the palms, forearms, fingers, knuckles, knees, feet, and sticks and stones to deliver a massage like a cat contracting its paws.  The traditional Lomilomi takes a lifetime to learn but many practitioners today claim to learn it in a few hours.  Traditional lomilomi involves prayer and herbal therapy also;  todays lomilomi is administered usually in homes, away from the offices of massage therapists and chiropractors, and involves dietary counseling.  

  • Naprapathy was established in the 1900s by a chiropractor Oakley Smith.  Naprapathic practice means the evaluation of persons with connective tissue disorders through and palpation or treatment of persons by the use of connective tissue manipulation, therapeutic and rehabilitative exercise, postural counseling, nutritional counseling, and the use of the effective properties of physical measures of heat, cold, light, water, radiant energy, electricity, sound and air, and assistive devices for the purpose of preventing, correcting, or alleviating a physical disability. 

  • Tui na  is a Chinese manipulative therapy used in conjunction with acupuncture, moxibustion, fire cupping, Chinese herbalism, t’ai chi, and qigong.  It is a hands-on body treatment using Chinese Taoist and martial arts principles where the practitioner may brush, knead, roll/press, and rub the areas between each of the joints, known as the 8 gates, to attempt to open the body’s defensive (wei) chi and get energy moving in meridians or muscles in a gentle to firm movement.  

  • Abhyanga massage is an Indian oil massage therapy as part of Ayurvedic medicine.  It uses copious amounts of oil and may be self massage or by a therapist. The benefits touted include increasing circulation to nerve endings, toning of muscles, lubrication of joints, increasing mental alertness, improving elimination of impurities from the body, better sleep, increased stamina.

  • Chavutti Thirumal is a massage where the therapist uses their feet to do this deep massage with oil.  The massage therapist stands above the patient holding onto a rope or rails. It was developed 3000 years ago by practitioners of Kalaripayattu, an Indian martial arts form.

  • Watsu is a pool massage therapy performed in chest-deep warm water.  A practitioner gently cradles, moves, stretches, and massages a client, and a progression of breath coordination, movement patterns in different position, and massage.  Cradling, rocking, dynamic stretching and mobilization, stillness, and mobilization techniques are focused on the needs of the receiver.

  • Manual lymphatic drainage  is a technique used for swelling or edema in extremities and is a gentle massage intended to encourage natural drainage of the lymph system.  It is the primary tool used in lymphedema management with certification available in the treatment.  It has mixed results in treatment of lymphedema, has no effectiveness in breast cancer lymphedema, and has some effect in skeletal muscle cell damage from sports injuries.   

  • Rolfing or structural integration is a technique founded by the work of Ida Rolf, a biochemist without any medical training in the 1930s.  Rolfing is performed in a progression of 10 sessions called “the recipe” that provides for the theorized alignment and movement of various body areas. Rolfing uses combinations of active and passive movement retraining. Also, see Structural Integration below.

  • Pfrimmer deep muscle therapy was the brainchild of one therapist, Therese C. Pfrimmer, (died in 1980) and subsequently there was a legal battle afterwards about who could teach the technique.  Pfrimmer  believed she was able to “relieve entrapped nerves, move out toxins, and bring lyphatic fluid towards “dry muscles”.  None of these have been scientifically proven.                                      

 

Massage therapy is effective for the treatment of fibromyalgia (PLoS One 2014 Feb 20;9(2). Swedish is more effective than Thai massage as a treatment of chronic low back pain (Complement Ther Med 2014 Feb;22(1):26-33)

PAINBYTES ASSESSMENT:  Other than reflexology and craniosacral therapy, in general massage is given a one thumbs up.  For certain particular therapies for pain situations, two thumbs up can be assigned.   Certain therapies such as Rolfing garner a neutral recommendation while acupressure, and reflexology are assigned a one thumb down due to the lack of science supporting the fundamental principles used in the technique.  Craniosacral is one thumb down due to “diagnostics” that may be erroneous and lead to incorrect or delayed diagnosis.  Deep tissue massage may worsen pain significantly in the chronic pain patient but in some it can be useful, therefore garners a neutral rating.

 

B.   Acoustic massage- uses transducers to induce acoustic or subsonic compression waves used for massage.  The Infratonic Qi-Gong machine was a device that  manufactured by the Infratonic Solutions CHI Institute that claims to have measured “energy vibrations from the hands of the qigong healers in Beijing China, something that apparently no one else seems to have been able to measure.  The company has since developed a series of sound wave machines that generate “noise” or random sound waves within a certain defined frequency range, the latest being the “Infratonic 9” costing $725 and their other machines cost $880.  These are generally not covered by insurance.  They make claims on their website that the 510(K) FDA approved device is useful for treatment of  pain, relieving subluxation (a chiropractic term), facilitate deep massage, enhances local circulation, increases energy level, relieves nerve impingement, relaxes muscles, reduces cellular trauma, dissolves cellular trauma, reduces inflammation, speed muscle cell healing, normalizes biochemical activity for accelerated healing.  They content “the therapy stops cells from sending pain signals and releasing inflammatory enzymes, which helps eliminate pain and inflammation”.  The research they cite are studies on horses, in children with asthma, and small studies of diabetic patients. Most of the studies are simply bizarre such as “Digestive Qi Deficiency in Children” and “Chaos and the College Entrance Exam”.  The authors make some very contentious assertions that seem to create their own science: that the therapy produces a highly unpredictable signal in the range of the brain’s EEG activity that is an important frequency range in which the body’s cells communicate with each other. (Never mind that the EEG is electrical signals while this device is mechanical producing compression waves, not electrical signals).   They also contend the “random signal easily penetrates the tissue’s vibrational defenses and interrupts the cellular communication that encourages inflammation, edema, chronic pain, and other abnormal cellular responses.”   It appears they have a bizarre understanding of physiology as there is no such thing as “vibrational defenses”.   What is highly likely is that making such claims of a device far exceeds the approval given by the FDA that approved the device as a massage device.   The website for these devices is www.soundvitality.com

While the Infratonic device uses white noise (random generated signals) within a frequency range, there are other devices that have been used for acoustical massage including the muscular acoustic modulator (MAM) is a device invented by Sandro Mandolesi a cardiologist.  This device uses a variable frequency of 0-400Hz with what appears to be an acoustic coil as in a loudspeaker, to deliver acoustic massage to painful muscles.  In controlled trials (small) there was a significant decrease in pain, to nearly zero, when the MAM device was used (BMC Geriatrics 2010, 10(Suppl 1):A111). 

Painbytes Assessment: Neutral- there simply aren’t enough high quality studies to demonstrate efficacy yet the technique does hold promise.  There does not appear to be any serious side effects.  This is not a technique in wide spread use.

C.   Graston technique- also known as instrument assisted cross fiber massage (IACRM) is a soft tissue mobilization technique using a series of rods and designed metal devices to deliver pressure across the fibers of the muscles, tendons, and ligaments as opposed to in-line with the fibers direction.  Effectively pressure (sometimes significant mechanical force) is delivered across the predominant soft tissue direction.   Practitioners tell patients they are breaking up scar tissue in tissue that has healed after injury, but frequently no clinically or radiologically detectable scar tissue in the area worked on by the practitioner.   Chiropractors and some physical therapists love these devices, some of which appear to be designed based on medieval tools of torture.  There is level C evidence of clinical effectiveness (weak clinical evidence) and there are some rat studies showing improved tissue perfusion days after the therapy is completed but not during the therapy.  This may suggest the rods and tools used may actually be causing tissue damage since increased vascular perfusion frequently follows soft tissue injury.     Graston is a “proprietary” technique and the practitioner must pay for special classes to become licensed in them and to use their curved tools and rods.  The quality of evidence of inducing the microscopic changes that the Graston practitioners tout is completely lacking in athletes and in humans.  There are a few anecdotal reflections in which the Graston practitioners did a series of treatments on athletes and they got better, but without controls or comparison studies it is impossible to differentiate these results from natural healing processes.  Some pilot studies showed no improvement at all.   Graston has been described by patients as “torture” as it is very painful. 

Painbytes assessment:  one thumb down.  Not enough science behind using very painful methods to break up “scar tissue” that is not detectable or non-existent.

D.  Hivamat therapy (deep oscillation therapy)- is a “massage therapy” that is proprietary and patented, available since 2007.  It is touted to promote faster healing of wounds, reduce cellulite, alleviate pain and swelling, lift and tone facial, bust, and buttock muscles, stimulate cell and collagen production for smooth younger looking skin, and improve skin tissue quality and elasticity.   The therapist massages the target area allowing the pulsed oscillations to penetrate your skin to a depth of 8-12cm through skin, connective tissue, subcutaneous fat, muscle, and blood vessels.  The website states it uses “electrostatic impulses” of 5 to 250 times creating a deep vibrational effect.  It is not clear what difference this is compared to variable frequency TENS units, and that the electrode is manually maneuvered over talc containing skin.  However on the website, it notes alternating current is being used, which is by definition not an electrostatic impulse, therefore there may be a misunderstanding of terminology since it is manufactured in Germany.  There is virtually no scientific proof of effectiveness and the “proof” cited by chiropractors and physical therapists are based on pilot studies that do not qualify as scientific studies.  There is both a unit used in clinics costing from $6,800 to $14,000, and a “personal” unit, the latter of which costs around $3000.  Of course it isn’t covered by some insurers including Aetna.

Painbytes assessment:  one thumbs down- machine expense (passed on to customers) and lack of proof of efficacy.

 

Meditation- see the listing under the Alt Therapy tab

 

Megavitamin therapy (also known as orthomolecular medicine)- The term “orthomolecular” was coined by the Nobel Lauriat Linus Pauling.  It is a neologism from the Latin meaning “correct molecules”, and is an alternative (not complementary) medicine philosophy that aims to maintain human health through nutritional supplementation.  Of course in the 1960s, nutritional supplements meant quite a different thing than they do today.  The orthomolecular medicine physicians date back to the 1930s when some doctors believed vitamins and supplements could cure diseases, even though the results were uniformly terrible.   Max Gerson developed a diet in the 1940s that he claimed cured diseases but the FDA in a series of studies demonstrated these claims were nonsensical. Megadoses of vitamin C were used as far back as 1948 and William McCormack touting this treatment that was later taken up by Linus Pauling himself.  Schizophrenia was treated with high doses of niacin in the 1950s and others used niacinamide without positive results. Orthomolecular medicine believes in dietary restriction, enormous doses of non-vitamin nutrients, doses of vitamins and amino-acids that are 10-1000 times that of the recommended daily doses (US RDA) in spite of such high doses being linked to increased risk of cancer, heart disease, and death.   Orthomolecular medicine does at times use mainstream pharmaceutical drugs, but not necessarily for their intended uses.  Orthomolecular doctors actually fabricated names for diseases such as pyroluria, histadelia, and histapenia, terms that do not exist in Western medicine.  Amino acid blood analysis is very important to doctors in orthomolecular medicine since they largely base their infusions of amino acids on these results.  The main uses of orthomolecular medicine are in treating schizophrenia, anti-aging, and advanced cancer- areas that are subject to fad therapies because treatments frequently are not compared to any controls.   When orthomolecular medicine is subjected to controls, frequently, the lack of effectiveness is demonstrated as with schizophrenia (Aust N Z J Psychiatry. 1999 Feb;33(1):84-8.) 

Studies on orthomolecular medicine are almost universally poorly constructed, consist of anecdotes, or opinions, and rarely tout any effective medical treatments, therefore alpha evidence of effectiveness is zero.  A link to learn more about this type of “medicine” is found at www.orthomolecular.org  

 

Meridian therapy- the meridians are imaginary energy pathways from the main organs of the body to the extremities (including the hands and feet).  Meridian theory goes back thousands of years to the ancient Chinese. A person trained in energy therapy is supposedly able to find tender points on the hands or feet, stick needles into them, electrify the needles, and cure inflamed or diseased internal organs.  Alternatively, acupressure is used on these points. The energy construct is the same mythical energy pathways as are used in acupuncture.  The concept of meridian therapy appeals to those that eschew science and prefer Eastern mysticism.   There is very little proof of meridians except in the Chinese literature that finds meridians and acupuncture to be highly effective, while in the Western literature the results are starkly different, usually with no significant difference at all compared to placebo.  Most Chinese studies fail to use a placebo control or their controls are erroneous leading to rosy results (J Acupunct Meridian Stud. 2016 Oct;9(5):227-233)

 

 

Mesotherapy-  also known as biorejuvenation or biorevitalization,  is a cosmetic procedure in which medications (vasodilators, antibiotics), vitamins, enzymes (collagenase, hyaluronidase), plant extracts, hormones (calcitonin, thyroxin), and homeopathic substances are injected 1-4 mm into the skin into the fat to tighten skin as well as remove excess fat.  The technique was developed by Michel Pistor, a French physician in 1952, and was originally used as a pain relief technique.  The injections are repeated every 7 days and repeated 3-15 times.  The evidence for this procedure has not shown significant benefit for skin rejuvenation.  A 2012 study (Int J Dermatol 2012 Aug;51(8):913-919) of 6 people receiving the treatment for 6 months showed no improvement in wrinkles and a 2008 study found no reduction in thigh size.

 

Micronutrient panel testing- see functional intracellular analysis

 

Millimeter wave therapy- the generation of electromagnetic waves of the 1-10 millimeter length level (Gigaherz waves) has been used for decades, primarily in Russia as a treatment for pain.  These waves are in the range 30-70 GHz with a power density of 10 mW/cm2, are non-ionizing, do not produce direct physical damage, nor produce any heating of the tissues.  In the US, it was theorized by Norm Shealy,, a pioneer in pain medicine, that a device for pain treatment patented by Kent in 1919 called Electreat operated in the GHz range, but this remained unproven and untested.  Millimeter wave therapy (MW) is usually placed on acupuncture points rather than directly over the injured tissue.   There are not many studies of MW but there is limited data to support its use in trigeminal neuralgia, joint pain, and headaches.  The machines are also used for weight loss.   Although the alpha level evidence is very sparce, there is an expansive review is located at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475937/

Mirror box therapy

 

Mistletoe (Iscador)-mistletoe is a semiparasitic plant growing on several common trees, and the extracts of mistletoe have been used since ancient times as a treatment for cancer.  The extracts are injected intravenously, subcutaneously, into the pleural cavity, or into the tumor itself.  There have been many human studies of mistletoe for the treatment of cancer, but nearly all the studies were flawed due to the lack of any controls, therefore no scientific conclusions could be drawn about its effectiveness.  It was introduced as a cancer treatment in 1921 by Rudolf Steiner (1861-1925), a self-proclaimed clairvoyant and Austrian mystic that founded the religion “anthroposophy” that forms the basis of the Waldorf education system.  In the 1960s, Vester and Nienhaus isolated cancer arresting protein fractions from mistletoe, the cytotoxic viscotoxins and mistletoe lectins.  Iscador is an European extract of the fermented plant and one of the most commonly used natural antitumor agents in Europe.  Due to the many commercially available preparations with drastically different components, it is difficult to determine any consistent effect that is due to the extracts.  In a meta-analysis, there is a positive effect of the extracts although it is difficult to quantify especially given the few randomized trials.  The randomized trials showed dramatically less effect on tumors compared to non-randomized trials.  Comparing iscador to placebo in lung cancer patients, there was no difference in survival.   In other cancers, iscador may have some effect.  To see an analysis of all the effects, see the study at www.ncbi.nlm.nih.gov/pmc/articles/PMC2804713/ 

 

Moxibustion – Burning the dried leaves of Mugwort produces a smoke that the Chinese believe open up the energy flow throughout the body, thereby healing the body. Moxibustion in the US typically involves a large smoldering stick of Mugwort held close to the surface of the skin.  Other ways smoldering Mugwort is used includes placement of the smoldering herb on the end of acupuncture needles or in small pots that are set on the surface of the skin in rows on the back. Moxibustion is part of the traditional Chinese medicine (TCM) system.  J Tradit Chin Med. 2014 Aug;34(4):392-400 Moxibustion was not superior to orthodox medicine in treatment of asthma.  Most moxibustion studies are of such low quality that for most conditions, no conclusions may be drawn as to the effectiveness.

Muscle strength testing- see applied kinesiology

Music therapy- Music therapy is the clinical and evidence-based use of music interventions to accomplish individualized goals within a therapeutic relationship by a credentialed professional who has completed an approved music therapy program.  Such therapy includes a broad range of activities such as listening to music, singing, and playing a musical instrument.  This type of therapy has demonstrated benefit in reducing anxiety and pain in patients undergoing a biopsy (J Adv Nurs 2017 Nov 23. Doi: 101111/jan. 13509).  When chosen by the patient, music therapy has a positive impact on chronic pain (Pain Physician 2017 Nov;20(7):597-610).  It also improves depression (Cochrane Database Syst Rev. 2017 Nov 16;11:CD004517)

Myofascial release: (see massage).  This hands-on technique seeks to free the body from the grip of tight fascia, or connective tissue, thus restoring normal alignment and function and reducing pain. Using their hands, therapists gently apply mild, sustained pressure to stretch and soften the fascia. Myofascial release is used to treat conditions such as neck and back pain, headaches, recurring sports injuries, and scoliosis.

 

Myotherapy- Myotherapy consists of assessing, treating, and managing the pain associated with soft tissue injury and restricted joint mobility which has been caused by myofascia or muscle dysfunction.  Effectively, it is a physical therapy technique that also may be used by massage therapists.  The theory of myotherapy includes myofascial release, that is fascia around muscles that has become stiff and scarred down, however there is no scientific evidence any such thing exists.  Myotherapy treats myofascial pain by mobilizing joints and muscles, helps with sore spots in the muscles, stiffness in the joints, and pins and needles focal sensations.  A “myotherapist” is a fancy name for someone who treats myofascial pain, and most legitimate practitioners avoid chic fad terms such as myotherapist.

Naturopathic medicine: This primary health care system emphasizes the curative power of nature and treats acute and chronic illnesses in all age groups. Naturopathic physicians work to restore and support the body's own healing ability using a variety of modalities including nutrition, herbal medicine, homeopathic medicine, and Asian medicine.  They eschew vaccinations and attempt to thwart the public vaccination programs.  Their training is very checkered with some having 1-2 year training programs and no residency while others have a 4 year training program without any residency.  Some will grind up plants and inject them intravenously.  Licensure is inconsistent with some states not requiring any licensure at all, yet they can prescribe medications including narcotics in some states.  They prescribe supplements calling them "natural" but in fact supplements as made in the US come from chemical stocks produced in chemical plants in China, and there is nothing "natural" about these substances.

Neural therapy (neural tension technique/electroneuromedular medicine)- Proponents of neural therapy believe that (i) the nervous system influences all bodily functions, (ii) energy flows freely through the body of a healthy person, and (iii) illness and chronic pain disrupt this flow of energy.  It involves the injection of anesthetics into various places of the body to eliminate pain and cure illness.  This method is not to be confused with nerve blocks and local anesthesia used in conventional medicine.  In neural therapy, anesthetics such as lidocaine and procaine, are injected into areas of the body that may be located far from the pain source.  These injections are meant to eliminate "interference fields" and restore the body's natural energy flow.  The injections may be given into nerves, acupuncture points, glands, scars, and trigger points.  A course of treatment may involve 1 or more injections spread over several weeks.  A few practitioners use electrical current and lasers instead of injected drugs.  Research into neural therapy has been done mainly in Germany where it is widely used; however, there is insufficient evidence on the effectiveness of neural therapy for pain management or for any other health problems (American Cancer Society, 2007).

Orgonomy-the study of “life energy”, named orgone energy by Wilhelm Reich (1897-1957) who made up the term and the name orgonomy.  Reich created his own lexicon describing “bions”, that were stated to be “tiny, highly-charged and very motile vesicles that were the transitional elements between life and non-life”.  He filmed these under a microscope therefore attempting to impart some science to these fantasies.  He stated the vesicles gather in clumps and form organisms, and there is a published book on “Experiments with the Microscope for the Amateur Orgonomist”.  Reich also found some of his “bions” gave out radiation that produced sensation in observers with “noticeable physical effects”.  He termed this radiation “life energy” which he named orgone after its origin in his study of orgasm function, and devised an apparatus to concentrate this energy called the “Orgone Accumulator”.  Reich elaborated this discovery into laying the foundation of orgonomic medicine, biology, physics, meteorology, and cosmology.   There is even an American College of Orgonomy.  However there are no scientific publications, and some websites go out of their way to chastise science for not accepting orgonomy at face value.  Orgonomy is used as a fringe psychological therapy.  Recommendation: avoid.   

Orthomolecular medicine- see megavitamin therapy

Ozone therapy-  Ozone is triatomic oxygen or O3 that has been used in medicine for decades, as a treatment for tuberculosis in 1892, as a surgical disinfectant, and more recently as a treatment administered to patients directly as an injection into the lumbar intervertebral disc or exiting nerve space, injection into joints, or by mixing with blood obtained from a patient followed by re-infusion back into the patient (autohemotherapy). It is a respiratory irritant and is toxic to the lungs, so breathing ozone as a medical treatment is not acceptable.  The FDA is so concerned about the proliferation of ozone usage in the US, they are attempting to regulate ozone generators (21CFR801.415).  There is scientific evidence to support its use as an injection into the disc, epidural space, muscles of the spine (Drug Des Devel Ther. 2015 May 15;9:2677-85,, Pain Physician. 2012 Mar-Apr;15(2):E115-29),  knee (J Orthop Surg Res. 2017 Jan 23;12(1):16).  There is some support for autohemotherapy in multiple sclerosis patients, gout, critical limb ischemia, as a means to prevent kidney reperfusion injury with surgery, dry macular degeneration, and preliminary results in the treatment of hepatitis C.

Photobiomodulation- see low level laser therapy

Pilates-is a movement therapy, very popular in the US, that consists of a system of exercises using special apparatus, designed to improve physical strength, flexibility, and posture, and enhance mental awareness.  It was developed in the early 20th century by Joseph Pilates, and he called it “Contrology”.  Classes are held at gyms, health centers, and in auditoriums, with a small fee attached to attend.  An exercise mat (frequently ¼-½” thick that is much thicker than the 1/8” thick yoga mats) are used.  Unlike yoga mats with their non-slide surfaces, pilates mats allow sliding on the surface. Pilates may be adapted to all ages and abilities.  Pilates has been shown to reduce pain and fatigue and increase range of motion in breast cancer patients compared to home exercise or no exercise (Rev Assoc Med Bras (1992). 2017 Nov;63(11):1006-1012).  Pilates mproves balance in older adults more than other exercise methods (J Aging Phys Act. 2017 Aug 3:1-21).   Pilates significantly improves low back pain and functional enhancement in those exercises including waist or torso movement, and Pilates performed for 20 or more cumulative hours (J Phys Ther Sci. 2016 Oct;28(10):2961-2969).  Painbytes assessment is two thumbs up for Pilates.

Polarity Therapy- this “energy” therapy was developed by Dr. Randoph Stone, a chiropractor and osteopath (DO) who was born in Austria in 1890 and died In 1981. He developed the idea that the body has “poles”, a positive charge at the head, and negative charge at the feet with a high frequency energy running between them called “life energy” or in other cultures called prana or chi.  These concepts have never been validated scientifically and remain conjecture.  He believed there is only one disease of the body- the blockage of energy from between the poles, and that all pain and illness is due to energy imbalance.  His method of correction of the disruption of energy flow is by holding the hands over the body or molding the hands around parts of the body, then combining with a rocking motion.  The therapist encourages the “energy to move” and can “break up congestion in the tissues and enliven the area”.  He also developed the “Stone Squat” and Polarity Yoga.  There is no scientific evidence this therapy has any validity or effect.  There were no scientific citations found in the national library of medicine database on polarity therapy.

Pranic therapy (Pranic Healing)- is a claimed energy healing system founded and promoted by Choa Kok Sui (1952–2007), a Filipino entrepreneur and philanthropist of Chinese descent. The healing modality claims that prana (energy) can heal ailments in the body by contributing to the person's energy field and uses major and minor chakras to do so.  Pranic healing uses techniques of breathing and visualization for quieting the mind, and for capturing and intentionally directing prana ("vital energy") wherever necessary.

Some nurses claim “When Pranic healing is applied the molecular structure of liquid and dense states of matter can be altered” (Aust J Holist Nurs 2004 Oct;11(2):35-40).   Of course, as with most of the alternative medicine therapies, there are different level courses that are required to become instructors, healers or masters.  Pranic courses include Pranic Crystal Healing, Pranic Psychic Self Defense, Pranic Healing and Advanced Pranic Healing, Pranic Feng Shui, Pranic Kriyashakti (harnessing the power of your thoughts and auric field to create a life of prosperity and financial success), Pranic Humming, Pranic Christianity, Pranic Buddhism, and other bizarre courses. 

There is no alpha evidence in the scientific literature.

There is one beta level evidence study of a positive adjuvant effect on depression (all patients were taking antidepressants)  with pranic healing over 5 weeks with 100% of patients improved with pranic healing and 69% of placebo patients (mock pranic healing).  There is significant bias in this study and the very high placebo response suggests any interaction with patients for 20minutes once a week results in positive response (Australas Psychiatry 2018 Feb;26(1):82-87). 

Gamma evidence (non controlled) demonstrated improvement in breast cancer patients in quality of life, pain, sleep, fatigue, social functioning, death ideation, and severity of mental disorders using pranic meditation twice a day for 8 weeks (Integr Cancer Ther 2014 Jul;13(4):341-50).  There is a uncontrolled study showing increased functionality of phagocytes by pranic meditation (J Altern Complement Med 2012 Aug;18(8):761-8)

Painbytes recommendation is a neutral given the small amount of evidence of effectiveness, but with a potential for significant benefit in psychological health at a low cost to patients and may be done at home.

Primal therapy-a trauma based psychotherapy created by Arthur Janov who believes neurosis is caused by the repressed pain of childhood trauma.  His technique involves re-experiencing specific incidents and fully expressing the resulting pain during therapy in order to bring the repressed pain into consciousness.  The therapy was very popular during the early 1970s but since has declined because of the lack of scientific research to support outcomes.

Prism Glasses- that shift the perceived location of the affected hand to the healthy side away from the midline in RSD (CRPS) caused an increase in temperature of the affected hand.  The amount of the increase was nearly 1 degree.  Prism glasses have potential applications in the treatment of one limb RSD.  (Pain 2013 Nov 154(11);2463-8)

Psychic Healing- psychic healing is often promised as an alternative medicine therapy.  There have been few tests of this questionable technique but one study on pain found no improvement of pain after psychic healing.  (J Psychosom Res. 2006 Jan;60(1):59-61).  Many of the energy based alternative medicine systems use psychic healing and therefore have been shown to be baseless. 

 

Qigong longevity exercises (chi-kung): Qigong is a coordinated body posture, movement, breathing, and meditation system.  This ancient Chinese exercise system aims to stimulate and balance the flow of qi (chi), or vital energy, along the acupuncture meridians, or energy pathways. Qi gong is used to reduce stress, improve blood circulation, enhance immune function, and treat a variety of health conditions. The Qi (vital energy) is combined with Gong (skill cultivated through steady practice).  Like Tai Chi, the exercise movements are slow and gentle, bringing muscle tone and increased flexibility to tendons and ligaments.There is evidence (alpha level) that qigong helps treat blood pressure in hypertensive patients (Pak J Pharm Sci. 2018 Jan;31(1):237-244., Medicine (Baltimore). 2017 Nov;96(45):e8517.)  There is a significant improvement in symptoms in cancer patients (Complement Ther Clin Pract. 2017 Nov;29:111-121).

 

Ream's testing- a nonsensical test of different properties of the urine that is supposed to diagnose 2,600 medical conditions.  Carey Reams (1910-1985) was a self-proclaimed biophysicist prosecuted in the 1970s for practicing medicine without a license, developed the Reams test of urine and saliva in the 1960s, “guided by God”, and came up with a mathematical expression based on perfect health based on the biophysical frequencies of living matter.  This mathematical expression was called by another fraudulent nutritionist “your Nutripathic Profile”.  The expression was in the form 1.56.4/6.4713/3.  The first three numbers represent the sugars excreted in the urine and the acidity of the urine and saliva, and indicate your “energy level”.  Other numbers represented the “mineral salt index, urine debris index, and nitrate nitrogens indicating how much energy your metabolism uses.  A low energy input and high energy drain means “degeneration, rot, decay, and death”.  Of course the entire theory behind the testing is wrong and is contradicted by science.  These kits available online for $295 are fraudulent and have no basis in diagnosis or treatment.

Reflexology: Also known as "zone therapy", this philosophy is based on the idea that specific points on the feet and hands correspond with organs and tissues throughout the body. With fingers and thumbs, the practitioner applies pressure to these points to treat a wide range of stress-related illnesses and ailments.  Reflexology as a therapy (foot massage) has been found to lower the anxiety of pregnant women ( Altern Complement Med. 2018 Feb 23.) and decreased pain and anxiety after abdominal hysterectomy (Complement Ther Med. 2018 Feb;36:107-112.)  There is little evidence reflexology has any benefit to distant organ health or as a diagnostic tool.

Reflex Therapy- see Spinal Reflex Therapy

Regenokine therapy- this is effectively a name brand used for platelet rich plasma (PRP) therapy, a commonly used method for treatment of various inflammatory and joint diseases.  Typically PRP involves spinning down a persons blood and then aspirating or decanting off the layer rich in platelets, then injecting them back into the patient’s inflamed area.  Regenokine refers to the trademarked sequence of the process and the equipment used to perform the process, however there are no studies identified by the National Library of Congress specifically using Regenokine, and it is only an assumption that other PRP studies apply to the Regenokine procedure.  Doctors using Regenokine typically report a 75% success rate- a far higher rate reported in the literature, therefore Regenokine statistics may simply be marketing hype.   Alpha level evidence shows the early results of small studies involving PRP are not reproducible or supported by higher level studies, randomized controlled trials, in treatment of acute muscle injuries (Sports Med. 2018 Jan 23.)  There is support for small improvements in short and long term pain in tendon and ligament injuries (Am J Sports Med. 2017 Dec 1:363546517743746).  The highest level studies show a significant improvement in the treatment of osteoarthritis of the knee (Int J Rheum Dis. 2017 Nov;20(11):1612-1630.)  There is very low quality evidence PRP helps with wound healing or plantar fasciitis.   As with other interventions, Chinese-author studies typically report much better outcomes in their reviews than non-Chinese authors and publications- suggesting a culture bias by Chinese authors.Reflex Therapy

Reiki -The very origin of Reiki is questionable. Some practitioners claim this is an ancient Tibetan healing system while other sources state it originated with a Buddhist schoolteacher in Japan in the mid 1800s.  In practice it uses light touch hand placements on the patient or above the patient to channel healing energies to the recipient. Practitioners attempt to “redirect the body’s spiritual energy”  Some practitioners that are more mercenary, will employ “Reiki by phone” for a fee, of course.  Reiki practitioners may vary widely in technique and philosophy, Reiki commonly is used to treat emotional and mental distress and chronic and acute physical problems and to assist the recipient in achieving spiritual focus and clarity.  There is little alpha level evidence Reiki has any benefit in physical healing of the body.  One study of Reiki on healing of wounds for very mixed results (Cochrane Database Syst Rev 2016 Aug 23;(8) with all studies at high risk for bias.  Reiki was specifically “not recommended” as a treatment for fibromyalgia syndrome (Schmertz 2012 Jun;26(3):311-17).  A review of randomized controlled trials with Reiki found “the evidence is insufficient to suggest that Reiki is an effective treatment for any condition” (Int J Clin Pract 2008 Jun;62(6):947-54.  On the other hand, there are many very positive Reiki studies that are uncontrolled (no placebo or comparison arm) suggesting strongly that Reiki functions primarily as a placebo effect itself, or the “power of suggestion” may convince unwitting patients of its usefulness.  There is also a profoundly strong bias in most of these exuberantly positive studies that invalidate most of the studies. (same person administering Reiki is collecting the results and analysis)  

Remedial massage- Practitioners of this therapy try to differentiate themselves from other massage therapists by taking a clinical approach to diagnosis of the cause of the problem with muscles, tendons, and ligament producing pain before initiating the massage.  They take a detailed history (unlike most massage therapies) and observe range of motion of various parts of the body.  If there is a limitation of a range of motion or a specific habit or body posture/movement of the patient that can cause the pain, then they employ techniques to correct not only the pain at a location, but also the predisposing factors for the pain.  Some of the techniques employed are myofascial release, mobilization of the spine, and cross fiber friction therapy.  Some of these therapies may cause some pain at the time they are employed.  Although there are no medical publications in the National Library of Medicine database with the term "Remedial massage", this technique is a type frequently employed by physical therapists and chiropractors as a form of kinesiotherapy and is an expansion of classical massage technique that includes diagnosis and etiology identification. 

Revici's guided chemotherapy - is an ineffective cancer treatment devised by Emanuel Revici (1896–1997).  Revici's early work on experimental chemical-based treatments for cancer between 1920–1941 attracted a degree of support. However his work increasingly found disfavor with the scientific and medical communities and his license was revoked in 1993. Revici's Guided Chemotherapy is based on the idea that all illness is caused by an "imbalance" of metabolism and these illnesses (including cancer) may have a predominance of one group of lipids (sterols) or the opposite (fatty acids).  He believed the former was anabolic or constructive and the latter to be catabolic or destructive. By using urinalysis (specific gravity, pH, surface tension) and blood test results, he prescribed substances of his own formulation that were designed to correct the “offbalance” in the body.  The treatment is giving a mixture of chemical substances that wer “anabolic” including lipid alcohols, lithium, zinc, iron, caffeine) or catabolic (fatty acids, sulfer, selenium, and magnesium).  Patients were told how to test their urine at home to alter their therapy from catabolic to anabolic and vice versa. These substances were taken by mout or by injection.  The American Cancer Society notes that this "chemotherapy" is entirely different from modern conventional chemotherapy, and states: "Available scientific evidence does not support claims that Revici's guided chemotherapy is effective in treating cancer or any other disease. It may also cause potentially serious side effects."  The American Cancer Society specifically recommended in 1989 that patients avoid such treatments.  Typically the patients that were seeking treatment using this method had advanced cancer or AIDs that had failed traditional medical treatment.  Because Revici failed to publish results of his medical treatment and failed to use standard measures of successful treatment, he did not garner the support of the medical community. The treatment is considered experimental in spite of 60 years of its use.

 

Rife therapy/Rife machine- Royal Raymond Rife, an American scientist developed in the 1920s a machine called the Rife frequency generator that generates low energy electromagnetic waves.  He claimed each disease has its own frequency, and tuning a frequency generator to the same frequency will kill or disable diseased cells.  He also believed all cancer is caused by bacteria, and claimed his machine could detect the bacteria by the color of the auras they emitted.  Pads are placed on the hands or feet for a few minutes a day, several times a week.  The cost of the machines are typically $300-3000.  The machines are not approved by the FDA, have no scientific proof of effectiveness, and are effectively a scam perpetuated on those easily duped.  The machine would have all but disappeared but for a conspiracy theory book called “The Cancer Cure that Worked!: Fifty Years of Suppression” published in 1987 that claimed all reports describing the cure were censored by the head of the AMA from publication in all medical journals.  

Rolfing- see Structural Integration

Rubenfeld synergy method (RSM)- is a trademark for a primarily emotional counseling method that combines talk and light touch “to put the body, mind, emotions and spirit in conversation with each other”.   RSM was created by Ilana Rubenfeld about 1968 after suffering shoulder pain, working with an Alexander therapist and Moshe Feldenkrais, and worked with Fritz and Laura Perls the psychotherapists behind Gestalt therapy. She combined all she had learned to create RSM.  Early on, she called her method “Gestalt Synergy” (Sante Ment Que 1980;5(1)-92-103).  In 1977 she opened a RSM professional training program.   RSM therapists call themselves “Synergists”.  The clients lie fully clothed on a bodywork table or sit in a chair, and the “synergists” use guiding talk and gentle touch to “help clients become more aware of their bodies, emotions, and stories”, “helping clients to stay with and explore sensations and emotions”.  The “synergists” listens and reflects what the clients are saying, moving the clients into “new understanding”, and the sensations become information that is used in the sessions.  It appears the major use of the RSM technique is for emotional trauma. There are only 51 “synergists” listed for the entire US on the rubenfeldsynergy.com website.  Their website has a section the “science behind RSM” that is populated only with non-scientific statements by synergists about the method.  There are no published scientific papers on the RSM in the National Library of Medicine database.  Without the science to support its use, it is recommended to avoid therapies that have no medical or scientific validation.

714-X (for cancer)  This drug is a completely experimental alternative therapy drug derived from mixing chemicals with camphor (from the bark of the camphor tree), and was developed in Canada in the 1960s.  The theoretical basis is that the camphor is said to prevent cancer cells from taking nitrogen from the body’s normal cells, and aid the immune system by increasing the flow of lymp.  It is administered by injection near the lymph nodes in the groin or for those with oral or nasal cancer, via nebulizer.  There are animal model studies using a lymphosarcoma tumor model in rats and lymphoma tumor models in dogs and cows, but 714-x was found not to be effective.  There are no human published studies of clinical trials.  (www.ncbi.nlm.nih.gov/books/NBK65771/#CDR0000446580_2) .  This is a completely experimental drug used by those who are desperate or those that irrationally believe “natural” products are better for them.  This treatment should be avoided.

Shiatsu: The most widely known form of acupressure, shiatsu has been used in Japan for more than 1000 years to treat pain and illness and for general health maintenance. Using a series of techniques, practitioners apply rhythmic finger pressure at specific points on the body to stimulate chi, or vital energy.

Sonic Massage Therapy- see acoustic massage under massage above

Spinal Reflex Therapy- Also called SRT, this is a chiropractic, physical therapist, or massage therapist treatment for a made-up diagnosis called "Spondylogenic Reflex Syndrome" or SRS.  Ostensibly this syndrome is demonstrated by throwing cold water on a person's back and watching the arching of the back and withdrawal from the cold water.  The extrapolated theory that requires significant flight of fancy and suspension of physics, is that long term muscle pain is caused by SRS and can only be treated by SRT.  SRS results in Profound pain and dysfunction, muscle spasms and weakness, fatigue, trigger points, soft tissue fibrosis, joint strain, degenerative arthritis, distorted posture, pinched nerves, acute and chronic pain, suppressed organ and immune responses.  It's origin is proposed to be due to poor ergonomics, diet, injury, weakness, stress, and other diffuse causes.  Of the millions of published medical articles, there are none containing the phrase "Spinal reflex therapy", therefore this is a quack therapy, manufactured by practitioners solely for the purpose of deluding the public.

Structural integration: Also known as Rolfing, this ten session technique of very deep tissue massage was developed by Ida Rolf (1896-1979), a biochemist with no training in physical therapy, kinesiology, chiropractic, massage, or medicine.  She developed her technique based on yoga exercises and gained her understanding of the body from her yoga instruction (from her obituary in the NY Times) in addition to studying homeopathy.  Structural integration was her term to describe a systematic approach to relieving patterns of stress and impaired functioning, structural integration seeks to correct misalignments in the body created by gravity and physical and psychological trauma. As in Rolting, in ten sessions the practitioner uses hands, arms, and elbows to apply pressure to the fascia, or connective tissue, while the client participates through directed breathing.  “Rolfers make a life study of relating bodies and their fields to the earth and its gravity field, and we so organize the body that the gravity field can reinforce the body’s energy field.”  Rolfing assumes dysfunction of the body is due to the body’s lack of harmony of its energy with gravity, and results in thickened and scarred fascia (the tough layer around muscles) although it has never been scientifically demonstrated this actually occurs. “It's a theory that is largely taken on faith, many researchers say. Wolf Mehling is a manual medicine physician at the University of California, San Francisco who treats patients with Rolfing as well as other kinds of massage. Still, he says, it's hard to say if Rolfing can lead to long-term structural changes in the body. "To my knowledge, there has been no randomized, controlled trials comparing Rolfing with other types of massage or bodywork," he says.

According to Mehling and other researchers, the few studies that have been done are too limited or flawed to draw any conclusions about Rolfing's effectiveness.  (NPR Morning Edition Dec 6, 2010)  After the death of Ida Rolf, there was a war between those who had trained with her over what was “certified” Rolfing, that devolved into a trademark enforcement action.  Some splinter-groups that broke away from Rolfing in part due to these spats are Hellerworks, SOMA, KMI, Aston Patterning, and others.

Rolfing has been described by the New York Times (Oct 7, 2010) as “ It’s painful, very painful, emotionally and physically”

Rolfing basic certification requires 22 weeks of study at Boulder, Colorado at a cost of approximately $28,000 for tuition, fees, and housing, and the credits for study are not transferrable to colleges or universities, since it is not a school accredited by university or college accrediting organizations.

Despite 70 years of Rolfing practice, there are almost no randomized controlled trials or comparative trials- a testament to the salesmanship of Rolfers rather than being a scientifically or medically validated procedure.

Tapping Therapy- See Thought Field Therapy

Telomere testing- ostensibly is a measure of cellular health.  Many of these are mail-order tests that measure the length of the telomeres- the strands of DNA that make reproduction of cells possible.  However other genetic encodings have stronger effects on longevity and health than do telomere length.  For instance, non-whites have longer telomeres, but have a shorter life expectancy.  Therefore telomere length testing is not a good measure of either cellular health or longevity. Until refined, this test is considered irrelevant.

Thalassotherapy- the use of sea water in hydrotherapy in order to absorb minerals and iodine through the skin- a concept that lacks scientific evidence.  The therapy is applied in various forms, as either showers of warmed seawater, application of marine mud or of algae paste, or the inhalation of sea fogSpas make hot seawater and provide mud and seaweed wrapping services.

Therapeutic Eurythmy-movement therapy.  The word eurythmy comes from the Greek root meaning beautiful or harmonious rhythm.  From the 1600s to the 1800s in England, it meant rhythmical order or movement or graceful proportion and carriage of the body.  In 1911, the word was given new meaning by Austrian philosopher Rudolf Steiner, who with his wife developed drama performances at the Anthroposophical Society’s summer gatherings, and incorporated the art of movement into the dramas.  This art form was integrated into the Waldorf education system. Later it was incorporated into anthroposophic medicine, that contends humands have four aspects needing treatment: spirit, soul, life, and matter.  Eurythmy treats the “life” aspect and  involves movements that are adapted to the condition of the person being treated and may be conducted with the patient lying down.  It is claimed such therapy brings about “re-integration of body, soul, and spirit”.  There is no alpha level scientific evidence of effectiveness for this treatment but there are a few uncontrolled studies with positive results, but these are subject to bias of the authors.  The recommendation of this author is that Eurythmy may be an add-on to other therapies, but if expensive, should not be relied upon given the lack of scientific validation of method.  However there are a few low level studies that do support its use.

Therapeutic Touch: Popularized by New York University nursing professor Dolores Krieger in the 1970s, Therapeutic Touch is practiced by registered nurses and others to relieve pain and stress. The practitioner assesses where the person's energy field is weak or congested and then uses his or her hands to direct energy into the field to balance it.  Ironically, practitioners of Therapeutic Touch claim no touch is actually necessary, and therefore patients are not always touched, making the name of the therapy a misnomer. The healing in Therapeutic Touch takes place via a supposed physical process called “electron transfer resonance”, which physicist Alan Sokal describes as “nonsense”. A study in JAMA in 1998 found that practitioners of therapeutic touch could not detect the presence or absence of a hand placed a few inches above theirs when their vision was obstructed and in the 2008 book “Trick or Treatment” it was concluded the “energy field was probably nothing more than a figment in the imaginations of the healers”.  The American Cancer Society notes “Available scientific evidence does not support any claims that therapeutic touch can cure cancer or other diseases”. A year 2000 review of therapeutic touch found profound bias in the nursing profession and misinterpretation of the studies results as positive, even when the research indicated it was ineffective (J Nurs Scholarsh 2000;32(3):279-85).  However there is some alpha level evidence that therapeutic touch has a very small effect (average reduction of pain was 0.8 on a VAS scale of 1-10) but this study included “Healing touch”, “therapeutic touch” and Reiki, with most of the positive results being due to Reiki (Cochrane Database Syst Rev 2008 Oct 8;(4):CD006535)  Therapeutic touch is therefore more of a nursing profession “belief system” rather than a valid scientifically proven therapy.

Thermogenic therapy-  Production of an artificial fever as a therapy was used since 1919 to treat resistant infectious diseases, rheumatoid arthritis and Sydenham's Chorea, however with the onset of antibiotic usage these uses are no longer employed, and the therapy is not covered by insurance carriers or Medicare.  Thermogenic therapy has been used as a supplement based weight loss technique however randomized trials that included a multi-ingredient supplement containing caffeine, green tea extract, l-carnitine, evodiamine and other ingredients that purportedly enhance thermogenesis, found no weight loss or fat loss compared with placebo (J Sports Sci Med. 2017 Dec 1;16(4):459-467).  Such thermogenic weight loss supplements are associated with life threatening encephalopathies (Neurocrit Care. 2017 Oct 18.).

Thought field therapy (TFT) (also known as Callahan Techniques Training, Tapping Therapy, Meridian Energy Therapy)- TFT was developed by American psychologist Roger Callahan (1925-2013) in the 1980s with his first book on TFT published in 1985. Callahan terms his treatment "Thought Field Therapy" because he theorizes that when a person thinks about an experience or thought associated with an emotional problem, they are tuning into a "thought field." He describes this field as "the most fundamental concept in the TFT system," stating that it "creates an imaginary, though quite real scaffold, upon which we may erect our explanatory notions".  Perturbations are said to be precisely encoded information contained in the thought field; each deformation of a person's thought field is connected to a particular problem, and is activated by thinking about that problem. Callahan maintains that these perturbations are the root cause of negative emotions and that each perturbation corresponds to a meridian point on the body. In order to eliminate the emotional upset, Callahan says that a precise sequence of meridian points must be tapped. He posits that tapping unblocks or balances the flow of qi.  The treatment sessions last 15 minutes and need not be repeated.  Callahan contended that TFT was useful for treatment of PTSD, depression, anxiety, addiction, and phobia.

 

TFT applies imaginal exposure in combination with tapping on traditional Chinese acupoints.  TFT was first used as a treatment for anxiety disorders and traumatic memories, but has expanded for an large number of medical conditions.  Imaginal exposure consists of the therapist asking the patient to focus on the selected incident, and to make it as vivid as possible.  The therapist questions the patient as to what the patient sees, smells, who else is present, and the most frightening thought about the incident.  A Subjective Unit of Distress Scale (SUDS) developed by Wolpe using a scale 0-10 is used.  It is preferred the patients do the tapping themselves on defined acupoints on the face, hand, chest, and fingers.  Callahan also added a procedure that includes eye movements, counting and humming while tapping an acupoint on the edge of the hand.

There is no alpha level therapy, but there is beta level therapy (RCTs) that TFT is equivalent to cognitive behavioral therapy and better than no therapy for the treatment of agoraphobia both short and long term (Front Psychol. 2017 Jun 20;8:1027).  A RCT for TFT for anxiety treatment demonstrated significant improvement in the TFT group that was maintained at 3 and 12 months. (Explore (NY). 2012 Nov-Dec;8(6):331-8).  It should be noted there was a retraction of a 2001 article published by Callahan in the J Clin Psychology 2005 in which the editors retracted the 2001 article contending Callahan misinterpreted the literature on heart rate variability, and the editor subsequently questioned his claims and premises about TFT.   At this time, there is limited cautious support for the technique used in the treatment of anxiety and agoraphobia.

 

Trager approach- The Trager approach is a form of somatic education. Proponents claim the Trager approach helps release deep-seated physical and mental patterns and facilitates deep relaxation, increased physical mobility, and mental clarity. The founder, Milton Trager (1908-1997), called his work Psychophysical Integration. He was an athlete, dancer, and bodybuilder but also had a congenital spinal problem causing him pain. He began doing bodywork with no training and later worked under a variety of practitioner licenses, including an MD earned in Mexico at age 47 followed by 2 years residency in psychiatry.   He always denied he was a healer but said he had “this thing”.  Trager wanted western medicine to accept his proposed mind-body connection in treating challenging conditions such as postpolio, Parkinson's, and other neuromuscular conditions. Doctors reportedly referred patients to him and were surprised by the results, but "none seemed to consider his drugless treatments as effective as surgery or medication" and the medical approach to these conditions did not fundamentally shift away from them as he had envisioned.  Late in life, at the Esalen Institute, he was encouraged to begin teaching, which he did for the last 22 years of his life.  He co-founded the Trager Institute in 1980.  Trager Approach is based on the premise that discomfort, pain and reduced function are physical symptoms of accumulated tension that result from accidents, weak posture, fear, emotional blockages and daily stress. It focuses on reducing these unnatural patterns of movement and eliminating neuromuscular tension by using gentle, rhythmic rocking motions. 

At the beginning of a session, the practitioner enters into a state of meditation that Milton Trager originally termed "hook-up". From this state of mind, the practitioner uses gentle touch and a combination of passive and active movement with the intent of teaching the recipient how to move with less effort. The contact is gentle in a sense; it may be quite firm but is without strain or resistance. Regarding pain, Trager practitioners avoid causing pain, and attempt to contact the body in a way that allows the client to have decreased fear of pain and increased willingness to be present with the full range of sensations. Practitioners are taught to allow a tone of curiosity, playfulness, and effortlessness to guide their work. In addition to hands-on bodywork, clients are taught a series of movements called "Mentastics" to be performed with a certain mental attention. While doing these movements, the client is asked to explore how to move with the least tension and effort possible.  To become a certified Trager Practitioner requires 409 hours of training minimum plus continuing education workshops thereafter.  Thousands have been trained in the Trager method.

Scientific literature to support the Trager approach is lacking.  There is no alpha or beta level literature, but there are some small gamma level studies showing Trager helps headaches (Altern Ther Health Med. 2004 Sep-Oct;10(5):40-6).

Trichuris suis ova therapy- Whipworms found in pigs ingested by humans results in short term self limited colonization of human GI tract.  Early uncontrolled studies (no placebo) found an 80% response rate of Crohns disease to this treatment (Gut. 2005 Jan;54(1):87-90.), however controlled randomized trials for the same disease found no difference between trichuris suis and placebo (Journal of Crohn's and Colitis, Volume 11, Issue 4, 1 April 2017, Pages 390–399).  Similarly, treatment of allergic rhinitis using a RCT placebo controlled trial failed to find any therapeutic effect compared to placebo, and induced diarrhea in 33% of study patients and 2% of the placebo patients (J Allergy Clin Immunol. 2010 Jan;125(1):123-30.  A RCT for ulcerative colitis found 43% of the trichuris suis group had clinical improvement and 10% went into remission  compared to 17% and 4% for the placebo controlled group (Cochrane Database Syst Rev. 2014 Jan 20;(1):CD009400).  At this time the usefulness of the therapy appears to be validated only in the use for treatment of ulcerative colitis.

Tui Na- see massage

Ultrasound (US) therapy- Ultrasound 5-10 watts has been used by physical therapists for decades in the treatment of musculoskeletal conditions.

US for myofascial pain review of RCTS- found high levels of bias in the studies making the level of evidence very low.  US did significantly reduce pain intensity but had no effect on range of motion (J Pain Res 2017 Mar 7;10:545-555).   For rotator cuff disease, US significantly reduced pain and function compared to placebo, but only short term (Cochrane Database Syst Rev. 2016 Jun 10;(6):CD012225).   A RCT found US to be ineffective in the treatment of chronic low back pain (Ann Fam Med 2013 Mar-Apr;11(2):122-9).  A review of US for acute ankle sprains found minimal differences for true US vs sham US (Eur J Phys Rehabil Med 2012 Jun;48(2):325-34).  For treatment of knee osteoarthritis, a systematic review found a medium clinical effect on pain and physical function after ultrasound treatment.  The quality of the trials was low (Osteoarthritis Cartilage 2010 Sep;18(9:1117-26)

Vascular endothelial cells (VECs) therapy

Vibrational essences- these are derived from stems, roots, bulbs and buds of flowers, minerals/gems, animals, the environment, light sources such as the stars and moon, and other healing energies such as Reiki.  Vibrational essences are made by placing a plant or mineral or other substance beside (or sometimes in) a bowl of water, let it stand in the sun for a few hours, then bottled and preserved with brandy. No, folks, as bizarre as it may seem, I am not simply making this stuff up- those selling this stuff actually believe it.  Unlike essential oils or aromatherapy, these vibrational essences are watered down and preserved with brandy.  Sometimes they are produced in a liquid form, sometimes in an ointment/crème form, and have no odor nor any flavor.  Users are encouraged to drink this stuff.  According to the manufacturer- “Vibrational essences create a shift in awareness within the individual by strengthening and balancing their subtle bodies. They focus on their surrounding energy bodies, as well as the individual cells and chakras of the physical body. When an essence is used, it sets up internally a vibration that corresponds to the healing being asked for. For example, the gem essence Rose Quartz may be used to assist someone searching for love to find a love of their higher self and the love that the universe has for them.”   There are no alpha or beta studies to support the use of these bizarre products.

Visceral manipulation therapy-  The French osteopath and physical therapist Jean Pierre Barral claims manipulation of the visceral organs will treat neck pain, traumatic brain injuries, seatbelt injuries, GERD, bloating, nausea, chronic pelvic pain, carpal tunnel syndrome, chronic spinal dysfunction, endometriosis, bladder incontinence, and many other diseases and conditions.  Scientific evidence for these claims is clearly lacking for nearly all his claims.  The only randomized controlled trials demonstrate a much more subdued enthusiasm for the technique.  Barral has training programs for the technique, primarily in Europe.

A RCT for low back pain demonstrated no difference in visceral manipulation at 2 and 6 weeks but there was a significant difference at one year.  (Eur J Pain. 2015 Aug;19(7):899-907.)  Another study used osteopathic manipulation in 19 patients and in another 20 patients both osteopathic manipulation and visceral manipulation was used.  Both therapies were equal with the exception that energy levels were higher with the combined therapy, but the study was small and not powered enough to determine significant differences.  (J Back Musculoskelet Rehabil 2017;30(3):419-425)

Whitcomb technique- a chiropractic treatment (and claimed cure) for fibromyalgia.  Paul Whitcomb is a chiropractor who operated Fibromyalgia Relief Clinic in California, diagnosing fibromyalgia by his own technique of palpating behind the C-1 vertebrae- a technique not accepted by other chiropractors or the medical community.  He claimed:

  • The primary cause is head or neck trauma that results in changes in the alignment between the base of the skull (occiput) and the topmost neck vertebra (atlas) that narrows when the opening at the base of the skull through which the spinal cord passes.

  • This "pulls" the membranes (meninges) that surround the cord, which knocks the sympathetic nervous system" out of whack and results in symptoms that, together, are labeled as fibromyalgia.

  • The Whitcomb Technique aims to reduce the subluxation that causes the symptoms. . . . by freeing up the neurological structures that are being encroached upon, thus allowing the brain and spinal cord to return to normal function.

  • The typical three–times–a–week treatment the average chiropractic patient receives is not sufficient to accomplish this for Fibromyalgia patients. Two or three times a day over a period of eight to ten weeks (eight weeks usually works the best and is the standard for most patients).

  • Patients experience 90 to 100% relief, follow-up care is not needed in most cases.

Whitcomb claims that the symptoms of fibromyalgia include insomnia, anxiety, fatigue, emotional instability, depression, irritability, nervousness, mild to severe body pain, headaches, irritable bowel syndrome, rashes, trigeminal neuralgia, calcium deposits under the skin, and communication problems. He further claims that all of the glands can be affected, and that "because the nervous system controls the body and can affect all the systems," a "whole galaxy" of other symptoms can occur. Whitcomb's treatment protocol involves 14 neck manipulations per week for 8-12 weeks, with three on Mondays, Wednesdays, and Fridays, two on Tuesdays and Thursdays, and one on Sundays. In 2008, the cost was $7,000 in advance for the first two months and $3,500 for each additional month.  Whitcomb had his license revoked by the State of California in 2009 after finding him guilty of (a) repeated acts of clearly excessive treatment, (b) multiple acts of gross negligence (c) repeated incompetence, (d) defective charting, (e) disseminating false and misleading statements for the purpose of inducing patients to use his services.  Whitcomb changed the name of his clinics to Neurological Relief Centers and now has more than 200 clinics operating nationally 

There is no scientific evidence that either the diagnosis or the therapy using the Whitcomb technique has any validity. 

Whole body vibration

Wurn technique/Clear Passage therapy- This is a pair of husband/wife physical therapists who like many other physical therapists, name a technique after themselves, write a few low level studies without any controls, compare them to surgical outcomes, write a book, develop a franchise, and like McDonalds they are exporting this technique to the world.  They claim to be able to cure infertility, hip and back pain, abdominal adhesions, and an entire array of maladies with their mobilization therapy, really not very different claims that some other notorious physical therapy techniques.  There are ten publications in the scientific literature on this technique, none are randomized or are controlled trials.  They are of the nature “I did this technique to someone and they got better”, but of course they may have improved anyway or improved due to another therapy altogether unrelated to the “Wurn technique”.  Clear Passage is a solely owned company by the Wurns. 

Recommendation: while there is possible benefit to the therapy, it has no alpha level support or even beta level support.  The gamma level support makes outcomes speculative and subject to a placebo response. 

Yoga therapy: This emerging field of practice uses yoga to address mental and physical problems while integrating body and mind. Practitioners work one-on-one or in group settings, assisting clients with yoga postures, sometimes combined with therapeutic verbal dialogue.  There is moderate evidence yoga is beneficial in low back pain (Ann Intern Med. 2017 Apr 4;166(7):493-505). Hatha Yoga for osteoarthritis of the knee demonstrated significant improvement for pain relief (Grade B) and physical function (Grade C+) (Clin Rehabil. 2017 May;31(5):582-595).  Yoga has been shown to be effective in the treatment of PTSD (low level evidence Clin Psychol Rev. 2017 Dec;58:115-124.), chronic neck pain (moderate evidence of short term effect Clin Rehabil. 2017 Nov;31(11):1457-1465).  Yoga asanas are associated with reduced evening cortisol, waking cortisol, ambulatory systolic blood pressure, resting heart rate, high frequency heart rate variability, fasting blood glucose, cholesterol and low density lipoprotein, compared to active control (Psychoneuroendocrinology. 2017 Dec;86:152-168).   Yoga improves fasting blood sugar and HgA1C in diabetic patients (Prev Med. 2017 Dec;105:116-126).  Those practicing yoga have an increased incidence of muscle sprains and strains, with a 22% chance during a yoga session, and a 4.6% persistent prevalence during a one year period.  Yoga causes a 72% increase in meniscus injuries to the knees. J Sci Med Sport. 2018 Feb;21(2):147-154

 

Zero balancing: This is a method for aligning body structure and body energy. Through touch akin to acupressure, the practitioner seeks to overcome imbalances in the structure/energetic interface of the body, which is said to exist beneath the level of conscious awareness. Zero balancing is often used for stress reduction.

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